Acrylic Acid Ethyl Ester

Acrylic Acid Ethyl Ester

SCHEMBL1486045

C=C(CC=C(C)C(=O)O)C(=O)OCC.C=CC(=O)OCC

nearest known ligand 0.38

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.38
CYP2D6 P10635 2/20 0.37
CYP2C19 P33261 1/20 0.37
TSHR P16473 8/20 0.37
HPGD P15428 1/20 0.37
HCAR2 Q8TDS4 1/20 0.35
GLO1 Q04760 1/20 0.34
ALDH1A1 P00352 8/20 0.33
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
CYP3A4 P08684 2/20 0.33
HSD17B10 Q99714 1/20 0.33
THRB P10828 1/20 0.32
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Methyl Ester SCHEMBL1486038 0.92 CYP2D6 (0.39) NPSR1CYP2D6CYP2C19TSHRHPGD
Acrylic Acid Ethyl Ester SCHEMBL1486048 0.92 TSHR (0.35) NPSR1CYP2D6CYP2C19TSHRHPGD
SCHEMBL6386586 0.91 CYP2D6 (0.42) NPSR1CYP2D6CYP2C19TSHRHCAR2
Acrylic Acid Ethyl Ester SCHEMBL10578244 0.91 TSHR (0.45) NPSR1CYP2D6CYP2C19TSHRHPGD
Acrylic Acid Ethyl Ester SCHEMBL16333556 0.90 TSHR (0.51) NPSR1CYP2D6CYP2C19TSHRHPGD
Acrylic Acid Ethyl Ester SCHEMBL9698333 0.89 TSHR (0.33) NPSR1CYP2D6CYP2C19TSHRHPGD
Acrylic Acid Ethyl Ester SCHEMBL6017688 0.89 ALOX15 (0.35) NPSR1CYP2D6CYP2C19TSHRHPGD
Methacrylic Acid SCHEMBL9472728 0.88 CYP2D6 (0.40) NPSR1CYP2D6CYP2C19TSHRHCAR2
SCHEMBL7968697 0.86 ALDH1A1 (0.45) CYP2D6CYP2C19TSHRHPGDALDH1A1
SCHEMBL10892397 0.85 CYP2D6 (0.39) NPSR1CYP2D6CYP2C19TSHRHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1881780-B1 LONG WEARING GLOSSY COSMETIC COMPOSITION ELC MAN LLC (US) 2016-10-26 EP claimed
US-8932570-B2 Long-wearing glossy cosmetic composition ELC MANAGEMENT LLC (US) 2015-01-13 US claimed
US-20110073126-A1 Long-Wearing Glossy Cosmetic Composition ELC MANAGEMENT LLC 2011-03-31 US claimed
EP-1881780-A1 LONG WERAING GLOSSY COSMETIC COMPOSITION ELC Management LLC (US) 2008-01-30 EP claimed
WO-2006124706-A1 LONG WERAING GLOSSY COSMETIC COMPOSITION ELC MANAGEMENT LLC (US) 2006-11-23 WO claimed
US-20060257342-A1 Long-wearing glossy cosmetic composition ELC MANAGEMENT LLC 2006-11-16 US claimed
EP-1881780-B1 LONG WEARING GLOSSY COSMETIC COMPOSITION ELC MAN LLC (US) 2016-10-26 EP disclosed
US-8932570-B2 Long-wearing glossy cosmetic composition ELC MANAGEMENT LLC (US) 2015-01-13 US disclosed
US-20110073126-A1 Long-Wearing Glossy Cosmetic Composition ELC MANAGEMENT LLC 2011-03-31 US disclosed
EP-1881780-A1 LONG WERAING GLOSSY COSMETIC COMPOSITION ELC Management LLC (US) 2008-01-30 EP disclosed
WO-2006124706-A1 LONG WERAING GLOSSY COSMETIC COMPOSITION ELC MANAGEMENT LLC (US) 2006-11-23 WO disclosed
US-20060257342-A1 Long-wearing glossy cosmetic composition ELC MANAGEMENT LLC 2006-11-16 US disclosed