Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 12/20 | 0.42 |
| ▸ | FEN1 | P39748 | 3/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | CEL | P19835 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9406090 | 0.86 | TRPV3 (0.38) | OPRL1 | |
| SCHEMBL17108421 | 0.86 | TRPV3 (0.35) | OPRL1FEN1ALOX5AP | |
| SCHEMBL9406095 | 0.86 | TRPV3 (0.38) | OPRL1 | |
| SCHEMBL18538126 | 0.85 | CYP3A4 (0.40) | OPRL1FEN1ALOX5AP | |
| SCHEMBL12716502 | 0.84 | OPRL1 (0.39) | OPRL1FEN1ALOX5AP | |
| SCHEMBL26044763 | 0.83 | OPRL1 (0.33) | OPRL1 | |
| SCHEMBL27952428 | 0.82 | CEL (0.44) | OPRL1FEN1ALOX5APCELPTGDR2 | |
| SCHEMBL9247484 | 0.81 | TRPV3 (0.36) | OPRL1 | |
| SCHEMBL12821091 | 0.81 | ALDH1A1 (0.34) | OPRL1 | |
| SCHEMBL5837243 | 0.81 | TRPV3 (0.36) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420764-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2013-04-16 | — | — | US | disclosed |