Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.39 |
| ▸ | CHRNG | P07510 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CHRND | Q07001 | 1/20 | 0.39 |
| ▸ | QDPR | P09417 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15247784 | 0.91 | SLC6A3 (0.43) | ESR2SLC6A3RIPK1SLC6A2SLC6A4 | |
| SCHEMBL14173389 | 0.85 | SLC6A3 (0.42) | ESR2SLC6A3PDK2CYP3A4CYP2C9 | |
| SCHEMBL10014180 | 0.84 | ESR2 (0.48) | ESR2SLC6A3RIPK1SLC6A2SLC6A4 | |
| SCHEMBL14817246 | 0.83 | ESR2 (0.53) | ESR2QDPRPDK2 | |
| SCHEMBL13499937 | 0.83 | SLC6A2 (0.41) | SLC6A3RIPK1SLC6A2SLC6A4CHRNA1 | |
| SCHEMBL12806513 | 0.83 | SLC6A3 (0.41) | SLC6A3RIPK1SLC6A2SLC6A4CHRNA1 | |
| SCHEMBL11933082 | 0.81 | ACMSD (0.41) | SLC6A3SLC6A2SLC6A4PDK2CYP3A4 | |
| SCHEMBL14173385 | 0.81 | SLC6A3 (0.44) | ESR2SLC6A3 | |
| SCHEMBL22643268 | 0.81 | QDPR (0.56) | SLC6A3SLC6A2SLC6A4QDPR | |
| SCHEMBL7149585 | 0.80 | ESR2 (0.55) | ESR2QDPRPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420764-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2013-04-16 | — | — | US | disclosed |