Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.66 |
| ▸ | OSBP | P22059 | 5/20 | 0.66 |
| ▸ | OSBP2 | Q969R2 | 3/20 | 0.66 |
| ▸ | USP2 | O75604 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.66 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.66 |
| ▸ | RORA | P35398 | 3/20 | 0.56 |
| ▸ | NPC1L1 | Q9UHC9 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.55 |
| ▸ | GPR183 | P32249 | 1/20 | 0.55 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.55 |
| ▸ | CRYAB | P02511 | 1/20 | 0.52 |
| ▸ | HMGCR | P04035 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGAV | P06756 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31305863 | 0.91 | RORC (0.62) | RORCOSBPOSBP2USP2LMNA | |
| SCHEMBL10105385 | 0.91 | RORC (0.62) | RORCOSBPOSBP2USP2LMNA | |
| SCHEMBL22150297 | 0.90 | RORC (0.61) | RORCOSBPOSBP2USP2LMNA | |
| SCHEMBL26668061 | 0.85 | NR1H3 (0.67) | RORCOSBPOSBP2USP2LMNA | |
| SCHEMBL14602524 | 0.83 | POLA1 (0.53) | RORCOSBPOSBP2USP2LMNA | |
| SCHEMBL18167508 | 0.83 | RORC (0.58) | RORCOSBPOSBP2USP2LMNA | |
| SCHEMBL14641136 | 0.83 | POLA1 (0.53) | RORCOSBPOSBP2USP2LMNA | |
| SCHEMBL22032747 | 0.83 | RORC (0.58) | RORCOSBPOSBP2USP2LMNA | |
| SCHEMBL18167509 | 0.83 | RORC (0.58) | RORCOSBPOSBP2USP2LMNA | |
| SCHEMBL13391627 | 0.83 | POLA1 (0.53) | RORCOSBPOSBP2USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9173839-B2 | Anionic lipids and lipid nano-structures and methods of producing and using same | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2015-11-03 | — | — | US | disclosed |
| US-20130243688-A1 | ANIONIC LIPIDS AND LIPID NANO-STRUCTURES AND METHODS OF PRODUCING AND USING SAME | UNIV OKLAHOMA (US) | 2013-09-19 | — | — | US | disclosed |
| US-8420118-B2 | Anionic lipids and lipid nano-structures and methods of producing and using same | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2013-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130243688-A1 | ANIONIC LIPIDS AND LIPID NANO-STRUCTURES AND METHODS OF PRODUCING AND USING SAME | SGMS2, SGMS1, PHOSPHO1 | RORC 2485/4885OSBP 444/4885OSBP2 212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.