SCHEMBL1486517

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1486522	0.91	NMT1 (0.46)	MAPTCYP3A4NMT1SMN1; SMN2L3MBTL1
	SCHEMBL5618434	0.84	MAPT (0.41)	MAPTMEN1KDRKMT2ACYP3A4
	SCHEMBL1486577	0.84	F2 (0.47)	MAPTMEN1KDRKMT2ACYP3A4
	SCHEMBL1486504	0.83	MAPT (0.42)	MAPTMEN1KDRKMT2ACYP3A4
	SCHEMBL1486462	0.82	MAOB (0.42)	MAPTMEN1KDRKMT2ACYP3A4
	SCHEMBL1486452	0.82	PIN1 (0.43)	MAPTMEN1KMT2ANMT1RAB9A
	SCHEMBL4067389	0.81	CYP3A4 (0.40)	MAPTMEN1KDRKMT2ACYP3A4
	Ammonia Solution, Strong SCHEMBL5618044	0.80	CYP3A4 (0.45)	MAPTCYP3A4GRM4NMT1MAOB
	SCHEMBL3873470	0.79	EGLN2 (0.44)	MAPTMEN1KDRKMT2ANMT1
	SCHEMBL4066173	0.79	ALOX5 (0.40)	MAPTMEN1KDRKMT2ANMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.