Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 6/20 | 0.34 |
| ▸ | KDR | P35968 | 5/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.34 |
| ▸ | FLT3 | P36888 | 2/20 | 0.34 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | LYN | P07948 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | HCK | P08631 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.34 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.34 |
| ▸ | ABL2 | P42684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3557591 | 0.70 | RAB9A (0.51) | METALDH1A1GAA | |
| SCHEMBL3561475 | 0.69 | RAF1 (0.47) | METKDRNTRK1EPHB4FLT3 | |
| SCHEMBL15458165 | 0.68 | KDR (0.51) | METKDRNTRK1EPHB4FLT3 | |
| SCHEMBL14865203 | 0.67 | KDR (0.37) | METKDRNTRK1EPHB4FLT3 | |
| SCHEMBL307269 | 0.65 | RAB9A (0.55) | ALDH1A1GAA | |
| SCHEMBL30074389 | 0.63 | HTT (0.54) | METALDH1A1GAA | |
| SCHEMBL2413206 | 0.62 | AXL (0.56) | METKDRFLT3PDGFRBAXL | |
| SCHEMBL13635722 | 0.62 | MET (0.53) | METKDRNTRK1EPHB4FLT3 | |
| SCHEMBL2151713 | 0.61 | HTT (0.49) | METALDH1A1GAA | |
| SCHEMBL28520687 | 0.61 | THRB (0.51) | METALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2058302-B1 | METHOD FOR PRODUCING PHENOXYPYRIDINE DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2013-04-17 | — | — | EP | disclosed |