Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2806172 | 0.91 | POLB (0.43) | POLBEPHX2MAPTCYP2C9SCN9A | |
| SCHEMBL13128411 | 0.83 | POLB (0.45) | POLBEPHX2MAPTCYP2C9MEN1 | |
| SCHEMBL13128471 | 0.81 | CTDSP1 (0.39) | POLBEPHX2MAPTCYP2C9SCN9A | |
| SCHEMBL2809250 | 0.78 | ALDH1A1 (0.41) | POLBMAPTCYP2C9ALDH1A1HPGD | |
| SCHEMBL185966 | 0.78 | BDKRB1 (0.40) | POLBMAPTCYP2C9ALDH1A1HPGD | |
| SCHEMBL2806680 | 0.78 | RAB9A (0.39) | POLBCYP2C9MEN1KMT2AGAA | |
| SCHEMBL13128461 | 0.78 | CTDSP1 (0.36) | POLBEPHX2CYP2C9SCN9A | |
| SCHEMBL185673 | 0.77 | POLB (0.45) | POLBEPHX2MAPTCYP2C9USP2 | |
| SCHEMBL2806861 | 0.77 | SMN1; SMN2 (0.40) | POLBEPHX2SCN9ASSTR4MEN1 | |
| SCHEMBL2807722 | 0.76 | CTSL (0.44) | POLBEPHX2MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |