Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 6/20 | 0.35 |
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
| ▸ | CTSS | P25774 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186506 | 0.94 | AR (0.38) | KCNQ3KCNQ2ARCTSKCTSS | |
| SCHEMBL186730 | 0.83 | TRPA1 (0.40) | TRPA1BDKRB1 | |
| SCHEMBL186050 | 0.82 | CNR1 (0.36) | KCNQ3KCNQ2TRPA1BDKRB1 | |
| SCHEMBL186398 | 0.82 | HDAC1 (0.35) | ARCTSKCTSSEPHX2CTSL | |
| SCHEMBL186387 | 0.82 | KCNQ3 (0.42) | KCNQ3KCNQ2BDKRB1 | |
| SCHEMBL185570 | 0.82 | ALDH1A1 (0.36) | TRPA1BDKRB1 | |
| SCHEMBL2807486 | 0.81 | HDAC3 (0.41) | TRPA1BDKRB1 | |
| SCHEMBL2811921 | 0.80 | HDAC3 (0.38) | CTSKCTSSTRPA1BDKRB1 | |
| SCHEMBL185915 | 0.80 | ABL1 (0.38) | CTSKCTSSBDKRB1 | |
| SCHEMBL2805859 | 0.80 | BDKRB1 (0.41) | ARTRPA1BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |