Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14865435 | 0.88 | TGFBR1 (0.33) | TGFBR1 | |
| SCHEMBL19998248 | 0.82 | KDM4E (0.37) | KDM4EMAPK1HIF1AKEAP1NFE2L2 | |
| SCHEMBL16803277 | 0.82 | KDM4E (0.37) | KDM4EMAPK1HIF1AKEAP1NFE2L2 | |
| SCHEMBL907569 | 0.81 | KDM4E (0.52) | KDM4EMAPK1HIF1ATGFBR1PAOX | |
| SCHEMBL632876 | 0.81 | KDM4E (0.46) | KDM4EMAPK1HIF1ATGFBR1PAOX | |
| SCHEMBL59429 | 0.79 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXMEN1 | |
| SCHEMBL8775499 | 0.79 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXMEN1 | |
| SCHEMBL16309325 | 0.79 | KDM4E (0.44) | KDM4EMAPK1HIF1ATGFBR1PAOX | |
| SCHEMBL8775297 | 0.79 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXMEN1 | |
| SCHEMBL8775294 | 0.79 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468715-B1 | Novel compound and method for preparing the same | FUJIFILM CORP (JP) | 2013-04-17 | — | — | EP | disclosed |