Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 5/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14865447 | 0.92 | ALDH1A1 (0.36) | OPRL1ALDH1A1LMNACNR2CNR1 | |
| SCHEMBL14865314 | 0.86 | CNR2 (0.34) | OPRL1CNR2CNR1HDAC1CA1 | |
| SCHEMBL2813417 | 0.82 | BDKRB1 (0.41) | OPRL1ALDH1A1LMNACNR2HDAC1 | |
| SCHEMBL13128639 | 0.81 | BDKRB1 (0.40) | OPRL1ALDH1A1LMNACNR2HDAC1 | |
| SCHEMBL186503 | 0.81 | CNR2 (0.37) | OPRL1ALDH1A1CNR2HDAC1 | |
| SCHEMBL2811657 | 0.81 | CNR2 (0.37) | OPRL1ALDH1A1CNR2HDAC1 | |
| SCHEMBL2809544 | 0.81 | OPRL1 (0.39) | OPRL1ALDH1A1CNR2HDAC1 | |
| SCHEMBL2805738 | 0.81 | AR (0.39) | OPRL1ALDH1A1LMNACNR2CNR1 | |
| SCHEMBL2804935 | 0.80 | OPRL1 (0.38) | OPRL1CNR2CNR1HDAC1CA1 | |
| SCHEMBL2808552 | 0.80 | PTK2 (0.41) | OPRL1CNR2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401256-B1 | Compounds as bradykinin B1 antagonists | BOEHRINGER INGELHEIM INT (DE) | 2013-04-17 | — | — | EP | disclosed |