SCHEMBL14865664

SCHEMBL14865664

Cc1ccc(Oc2ccc(N)cc2C(F)(F)F)c(C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.44
GLA P06280 1/20 0.44
GAA P10253 1/20 0.44
TSHR P16473 1/20 0.44
SYK P43405 1/20 0.40
AR P10275 6/20 0.39
SCN10A Q9Y5Y9 1/20 0.37
HTR1A P08908 2/20 0.36
HTR3A P46098 2/20 0.36
ALDH1A1 P00352 2/20 0.36
CYP3A4 P08684 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
NR1H2 P55055 1/20 0.35
TEAD4 Q15561 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
MAPT P10636 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14865703 0.93 AR (0.45) POLBGLAGAATSHRSYK
SCHEMBL12261579 0.92 GAA (0.48) POLBGLAGAATSHRSYK
SCHEMBL12650711 0.92 POLB (0.48) POLBGLAGAATSHRSYK
Aniline SCHEMBL28416314 0.89 HTR1A (0.38) POLBGLAGAATSHRSYK
SCHEMBL15831196 0.89 AR (0.43) POLBGLAGAATSHRSYK
SCHEMBL12259251 0.89 SYK (0.49) GAASYKARSCN10AHTR1A
SCHEMBL27821176 0.86 AR (0.44) POLBGLAGAATSHRAR
SCHEMBL29404322 0.85 GAA (0.59) POLBGLAGAATSHRSYK
SCHEMBL436804 0.85 GAA (0.59) POLBGLAGAATSHRSYK
SCHEMBL12689579 0.84 POLB (0.44) POLBGLAGAATSHRAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230229080-A1 PHOTOSENSITIVE COMPOSITION AND FILM PREPARED FROM THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2023-07-20 US disclosed
US-20170298198-A1 AROMATIC POLYAMIDE FILMS FOR SOLVENT RESISTANT FLEXIBLE SUBSTRATES SUMITOMO BAKELITE CO., LTD. (JP) 2017-10-19 US disclosed
US-20160369053-A1 POLYIMIDE RESIN AND METAL-CLAD LAMINATE COMPRISING THE SAME ETERNAL MATERIALS CO., LTD. (TW) 2016-12-22 US disclosed
US-20160208096-A1 SOLUTION OF AROMATIC POLYAMIDE FOR PRODUCING DISPLAY ELEMENT, OPTICAL ELEMENT, ILLUMINATION ELEMENT OR SENSOR ELEMENT AKRON POLYMER SYSTEMS, INC. (US) 2016-07-21 US disclosed
US-20160111696-A1 METHOD FOR MAKING POLYIMIDE MICROPOROUS SEPARATOR TSINGHUA UNIVERSITY (CN) 2016-04-21 US disclosed
US-20140175683-A1 AROMATIC POLYAMIDE FILMS FOR SOLVENT RESISTANT FLEXIBLE SUBSTRATES AKRON POLYMER SYSTEMS, INC. (US) 2014-06-26 US disclosed
US-8673540-B2 Photosensitive polymides ETERNAL CHEMICAL CO., LTD. (TW) 2014-03-18 US disclosed
US-20130095426-A1 PHOTOSENSITIVE POLYMIDES ETERNAL CHEMICAL CO., LTD. (TW) 2013-04-18 US disclosed