Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL15771252 | 0.97 | TP53 (0.39) | TP53KDM4EALDH1A1TDP1PSIP1 | |
| Hydrochloric Acid SCHEMBL15771447 | 0.97 | TP53 (0.39) | TP53KDM4EALDH1A1TDP1PSIP1 | |
| Hypophosphorous Acid SCHEMBL31464982 | 0.86 | SMN1; SMN2 (0.35) | TP53ALDH1A1PSIP1LMNATRPA1 | |
| SCHEMBL27922779 | 0.85 | LOXL2 (0.35) | TP53SMN1; SMN2 | |
| SCHEMBL27949753 | 0.81 | TAAR1 (0.34) | TP53SMN1; SMN2CYP19A1 | |
| SCHEMBL5080022 | 0.78 | TP53 (0.38) | TP53KDM4EALDH1A1TDP1PSIP1 | |
| SCHEMBL149837 | 0.77 | TP53 (0.41) | TP53KDM4EALDH1A1TDP1PSIP1 | |
| SCHEMBL153865 | 0.74 | ACHE (0.44) | ALDH1A1TDP1LMNAACHEMAPT | |
| SCHEMBL11374639 | 0.74 | TP53 (0.39) | TP53KDM4EALDH1A1TDP1PSIP1 | |
| SCHEMBL6292784 | 0.74 | TP53 (0.39) | TP53KDM4EALDH1A1TDP1PSIP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 986 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746167-B2 | Process for the preparation of polyisoprene with a mainly alternating cis-1,4- alt-3,4 structure in the presence of a catalytic system comprising a pyridyl iron complex | VERSALIS S.P.A. (IT) | 2023-09-05 | — | — | US | claimed |
| US-20230250208-A1 | SYNTHESIS OF ISOPRENE-BUTADIENE COPOLYMER RUBBERS | MIZUHO BANK, LTD., AS ADMINISTRATIVE AGENT | 2023-08-10 | — | — | US | claimed |
| CN-111587259-B | Process for preparing polyisoprenes having predominantly alternating cis-1, 4-alternating-3, 4 structure | 维尔萨利斯股份公司 | 2023-07-11 | — | — | CN | claimed |
| CN-116082550-A | Cycloolefin copolymer based on dicyclopentadiene and preparation method thereof | 中国科学院长春应用化学研究所 | 2023-05-09 | — | — | CN | claimed |
| US-11597790-B2 | Synthesis of isoprene-butadiene copolymer rubbers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2023-03-07 | — | — | US | claimed |
| EP-3345940-B1 | MODIFIED CONJUGATED DIENE-BASED POLYMER AND METHOD FOR PREPARING THE SAME | LG CHEMICAL LTD (KR) | 2022-10-19 | — | — | EP | claimed |
| CN-113896846-B | Hydrogenated polyisoprene-embedded-syndiotactic poly (fluoro styryl) hydrophobic elastomer and preparation method thereof | 大连理工大学 | 2022-06-14 | — | — | CN | claimed |
| EP-3740517-B1 | PROCESS FOR THE PREPARATION OF POLYISOPRENE WITH A MAINLY ALTERNATING CIS-1,4- ALT-3,4 STRUCTURE IN THE PRESENCE OF A CATALYTIC SYSTEM COMPRISING A PYRIDYL IRON COMPLEX | VERSALIS SPA (IT) | 2022-06-08 | — | — | EP | claimed |
| CN-113136001-B | Preparation method of ethylene-fluorostyrene copolymer | 中国科学院长春应用化学研究所 | 2022-05-06 | — | — | CN | claimed |
| CN-113896846-A | Hydrogenated polyisoprene-embedded-syndiotactic poly-fluoro-styryl hydrophobic elastomer and preparation method thereof | 大连理工大学 | 2022-01-07 | — | — | CN | claimed |
| EP-1201687-B1 | Synthesis of elastomeric high trans-1,4-polybutadiene | GOODYEAR TIRE & RUBBER (US) | 2004-07-21 | — | — | EP | claimed |
| US-20030187162-A1 | Synthesis of polyisoprene with neodymium catalyst | GOODYEAR TIRE & RUBBER COMPANY, THE | 2003-10-02 | — | — | US | claimed |
| US-6617406-B2 | Catalyzing polybutadiene polymerization in presence of an organocobalt compound, an organoaluminum compound, a para-alkyl substituted phenol, and ortho-phenyl phenol; no heat needed during polymerization | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-09-09 | — | — | US | claimed |
| US-20030065114-A1 | Synthesis of elastomeric high trans-1,4-polybutadiene | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-04-03 | — | — | US | claimed |
| EP-1201687-A1 | Synthesis of elastomeric high trans-1,4-polybutadiene | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2002-05-02 | — | — | EP | claimed |
| US-6310152-B1 | CATALYTIC ADDITION POLYMERIZATION OF BUTADIENE USING ORGANOALUMINUM, ORGANOCOBALT AND PHENOL COMPOUND | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-10-30 | — | — | US | claimed |
| EP-0879833-A1 | Synthesis of trans-1,4-polybutadiene | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-11-25 | — | — | EP | claimed |
| US-5834573-A | POLYMERIZING 1,3-BUTADIENE IN THE PRESENCE OF A COBALT(III) ACETYLACETONATE, ORGANOALUMINUM COMPOUND, AND PARA-ALKYL-PHENOL CATALYST SYSTEM; GEL-FREE, MOLECULAR WEIGHT CONTROL; CARBON DISULFIDE ABSENT; TIRES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-11-10 | — | — | US | claimed |
| US-5451646-A | P-styrenated diphenylamine, nickel, aluminum, fluorine catalyst | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1995-09-19 | — | — | US | claimed |
| US-4663405-A | ADDITION POLYMERIZATION COORDINATION CATALYSTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1987-05-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746167-B2 | Process for the preparation of polyisoprene with a mainly alternating cis-1,4- alt-3,4 structure in the presence of a catalytic system comprising a pyridyl iron complex | AOC3, AOC2, C5 | TP53 4605/4885KDM4E 4169/4885ALDH1A1 2178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.