SCHEMBL1486580

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL311094	0.88	CYP3A4 (0.58)	IP6K1CYP3A4LMNACYP1A2PTGS1
	SCHEMBL30153587	0.88	CYP3A4 (0.58)	IP6K1CYP3A4LMNACYP1A2PTGS1
	SCHEMBL26355932	0.82	IP6K1 (0.56)	IP6K1CYP3A4PLAUPLATMAOB
	SCHEMBL30530239	0.82	IP6K1 (0.56)	IP6K1CYP3A4PLAUPLATMAOB
	SCHEMBL18685900	0.82	KDM4E (0.47)	IP6K1CYP3A4LMNACYP1A2PTGS1
	SCHEMBL3899573	0.82	IP6K1 (0.56)	IP6K1CYP3A4PLAUPLATMAOB
	SCHEMBL26355935	0.82	LMNA (0.64)	IP6K1CYP3A4LMNAPLAUPLAT
	SCHEMBL30530234	0.82	LMNA (0.64)	IP6K1CYP3A4LMNAPLAUPLAT
	SCHEMBL30440566	0.81	GRM4 (0.56)	IP6K1CYP3A4PLAUPLATMAOB
	SCHEMBL4748546	0.80	ERBB2 (0.49)	LMNAERBB2NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.