Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.58 |
| ▸ | CFD | P00746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 2/20 | 0.45 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.44 |
| ▸ | HNF4A | P41235 | 2/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 2/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70164 | 0.92 | MCL1 (0.66) | MCL1CFDKDM4EGFERKMT2A | |
| Hydrochloric Acid SCHEMBL9153007 | 0.90 | MCL1 (0.63) | MCL1CFDKDM4EGFERKMT2A | |
| SCHEMBL10024252 | 0.87 | MAPT (0.55) | MCL1CFDKDM4EGFERKMT2A | |
| SCHEMBL7125464 | 0.86 | MAPT (0.53) | MCL1KDM4EGFERACMSDHNF4A | |
| SCHEMBL4966627 | 0.84 | MCL1 (0.70) | MCL1CFDKDM4EGFERKMT2A | |
| SCHEMBL9154339 | 0.84 | MCL1 (0.62) | MCL1CFDKDM4EGFERKMT2A | |
| SCHEMBL5255978 | 0.84 | MCL1 (0.63) | MCL1ACMSDHNF4ADHFRAKR1C2 | |
| SCHEMBL10024279 | 0.84 | MCL1 (0.63) | MCL1ACMSDHNF4ADHFRAKR1C2 | |
| SCHEMBL10024260 | 0.83 | ACLY (0.49) | MCL1ACMSDHNF4ADHFRAKR1C2 | |
| SCHEMBL10024268 | 0.82 | MCL1 (0.61) | MCL1CFDKDM4EGFERKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9669098-B2 | Metal-organic frameworks with exceptionally large pore aperatures | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-06-06 | — | — | US | disclosed |
| US-20160008472-A1 | METAL-ORGANIC FRAMEWORKS WITH EXCEPTIONALLY LARGE PORE APERATURES | UNITED STATES DEPARTMENT OF ENERGY | 2016-01-14 | — | — | US | disclosed |
| US-9078922-B2 | Metal-organic frameworks with exceptionally large pore aperatures | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-07-14 | — | — | US | disclosed |
| US-20130096210-A1 | METAL-ORGANIC FRAMEWORKS WITH EXCEPTIONALLY LARGE PORE APERATURES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160008472-A1 | METAL-ORGANIC FRAMEWORKS WITH EXCEPTIONALLY LARGE PORE APERATURES | AP3M1, AP2M1, AP2A2 | MCL1 1336/4885CFD 2845/4885KDM4E 2242/4885 |
| US-20130096210-A1 | METAL-ORGANIC FRAMEWORKS WITH EXCEPTIONALLY LARGE PORE APERATURES | AP3M1, AP2M1, AP2A2 | MCL1 1336/4885CFD 2845/4885KDM4E 2242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.