Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.53 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.50 |
| ▸ | CFD | P00746 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 3/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | HNF4A | P41235 | 1/20 | 0.44 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 2/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14866633 | 0.87 | MCL1 (0.58) | MCL1HSD17B1CFDRXRBRXRA | |
| SCHEMBL70164 | 0.87 | MCL1 (0.66) | MCL1CFDRXRBRXRAAKR1C2 | |
| SCHEMBL12132604 | 0.85 | AKR1C3 (0.54) | AKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL10024260 | 0.85 | ACLY (0.49) | MAPTSMN1; SMN2MCL1AKR1C3AKR1C2 | |
| Hydrochloric Acid SCHEMBL9153007 | 0.85 | MCL1 (0.63) | MCL1CFDRXRBRXRAAKR1C2 | |
| SCHEMBL9154339 | 0.83 | MCL1 (0.62) | MCL1CFDRXRBRXRADHFR | |
| SCHEMBL10024279 | 0.83 | MCL1 (0.63) | MCL1AKR1C3AKR1C2DHFRHNF4A | |
| SCHEMBL5255978 | 0.83 | MCL1 (0.63) | MCL1AKR1C3AKR1C2DHFRHNF4A | |
| SCHEMBL27532814 | 0.83 | RXRA (0.55) | MAPTMCL1RXRBRXRAKDM4E | |
| SCHEMBL4966627 | 0.83 | MCL1 (0.70) | SMN1; SMN2MCL1CFDRXRBRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120083471-A1 | Novel Compounds, Pharmaceutical Compositions Containing Same, Methods of Use for Same, and Methods for Preparing Same | FAS SECURED CREDITORS HOLDCO, LLC | 2012-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120083471-A1 | Novel Compounds, Pharmaceutical Compositions Containing Same, Methods of Use for Same, and Methods for Preparing Same | LCAT, DGAT2, SOAT2 | MAPT 2464/4885SMN1; SMN2 3908/4885MCL1 4030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.