Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | STS | P08842 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14866647 | 0.99 | ALDH1A1 (0.41) | ALDH1A1MAPTNPC1RAB9ATSHR | |
| SCHEMBL14866908 | 0.96 | LMNA (0.42) | ALDH1A1MAPTNPC1RAB9ATSHR | |
| SCHEMBL19648689 | 0.94 | LMNA (0.40) | ALDH1A1MAPTNPC1RAB9ATSHR | |
| SCHEMBL14866748 | 0.92 | LMNA (0.43) | ALDH1A1MAPTNPC1RAB9ATSHR | |
| SCHEMBL12069809 | 0.88 | RAB9A (0.44) | ALDH1A1MAPTNPC1RAB9AESR1 | |
| SCHEMBL19648682 | 0.88 | MAPT (0.36) | ALDH1A1MAPTNPC1RAB9ATSHR | |
| SCHEMBL19648945 | 0.87 | MAPT (0.33) | ALDH1A1MAPTNPC1RAB9ATSHR | |
| SCHEMBL19648592 | 0.81 | HPGD (0.46) | ALDH1A1MAPTNPC1RAB9ATSHR | |
| SCHEMBL14866717 | 0.79 | TSHR (0.31) | ALDH1A1TSHRLMNAMAPK1TP53 | |
| SCHEMBL14866890 | 0.79 | MEN1 (0.34) | ALDH1A1MAPTLMNAMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9057020-B2 | Black dichroic dye | BASF SE (DE) | 2015-06-16 | — | — | US | disclosed |
| US-9057020-B2 | Black dichroic dye | BASF SE (DE) | 2015-06-16 | — | — | US | disclosed |
| US-20130092874-A1 | BLACK DICHROIC DYE | BASF SE (DE) | 2013-04-18 | — | — | US | disclosed |
| US-20130092874-A1 | BLACK DICHROIC DYE | BASF SE (DE) | 2013-04-18 | — | — | US | disclosed |