Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20052008 | 0.94 | POLB (0.52) | POLBHSD17B10 | |
| SCHEMBL13896530 | 0.89 | POLB (0.47) | POLBHSD17B10 | |
| SCHEMBL14867649 | 0.82 | POLB (0.31) | POLBHSD17B10 | |
| SCHEMBL14867637 | 0.81 | POLB (0.68) | POLBHSD17B10 | |
| SCHEMBL13443476 | 0.78 | POLB (0.52) | POLBHSD17B10 | |
| SCHEMBL14867658 | 0.77 | KDM4E (0.35) | — | |
| SCHEMBL20052005 | 0.76 | POLB (0.72) | POLBHSD17B10 | |
| SCHEMBL20052002 | 0.76 | POLB (0.32) | POLBHSD17B10 | |
| SCHEMBL14867641 | 0.75 | CCNB2 (0.32) | — | |
| SCHEMBL17445607 | 0.75 | POLB (0.47) | POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130096289-A1 | HYDROXYMETHYL SUBSTITUTED RNA OLIGONUCLEOTIDES AND RNA COMPLEXES | MARINA BIOTECH, INC. (US) | 2013-04-18 | — | — | US | disclosed |