Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20052007 | 0.96 | KDM4E (0.36) | KDM4EL3MBTL1MEN1TSHRKMT2A | |
| SCHEMBL17014883 | 0.87 | KDM4E (0.39) | KDM4EMEN1TSHRKMT2A | |
| SCHEMBL14867659 | 0.85 | KDM4E (0.39) | KDM4EL3MBTL1MEN1TSHRKMT2A | |
| SCHEMBL13443499 | 0.82 | L3MBTL1 (0.36) | KDM4EL3MBTL1MEN1TSHRKMT2A | |
| SCHEMBL20052006 | 0.82 | KDM4E (0.40) | KDM4EL3MBTL1MEN1TSHRKMT2A | |
| SCHEMBL14867641 | 0.82 | CCNB2 (0.32) | L3MBTL1 | |
| SCHEMBL20051998 | 0.78 | CCNB2 (0.35) | KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL13443496 | 0.77 | POLB (0.42) | KDM4EL3MBTL1MEN1TSHRKMT2A | |
| SCHEMBL14867638 | 0.77 | POLB (0.50) | — | |
| SCHEMBL14867649 | 0.76 | POLB (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130096289-A1 | HYDROXYMETHYL SUBSTITUTED RNA OLIGONUCLEOTIDES AND RNA COMPLEXES | MARINA BIOTECH, INC. (US) | 2013-04-18 | — | — | US | disclosed |