SCHEMBL14868196

SCHEMBL14868196

Brc1ccc2c(c1)c1cc(Br)ccc1n2-c1ccc2oc3ccccc3c2c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.42
▸ SMN1; SMN2 Q16637 3/20 0.42
▸ NPC1 O15118 3/20 0.42
▸ RAB9A P51151 2/20 0.42
▸ KDM4E B2RXH2 2/20 0.42
▸ MEN1 O00255 2/20 0.42
▸ ALDH1A1 P00352 2/20 0.42
▸ HPGD P15428 2/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ IDO1 P14902 1/20 0.40
▸ AHR P35869 2/20 0.39
▸ GABRP O00591 2/20 0.38
▸ GABRD O14764 2/20 0.38
▸ GABRA1 P14867 2/20 0.38
▸ GABRB1 P18505 2/20 0.38
▸ GABRG2 P18507 2/20 0.38
▸ GABRB3 P28472 2/20 0.38
▸ GABRA5 P31644 2/20 0.38
▸ GABRA3 P34903 2/20 0.38
▸ GABRA2 P47869 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12159648 0.97 SMN1; SMN2 (0.41) MAPTSMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL30445626 0.97 SMN1; SMN2 (0.41) MAPTSMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL12801043 0.94 KDM4E (0.41) MAPTSMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL13471423 0.92 PIM1 (0.40) MAPTNPC1RAB9AHPGDGABRP
SCHEMBL14868195 0.92 PIM1 (0.40) MAPTNPC1RAB9AHPGDGABRP
SCHEMBL16154912 0.92 TNKS (0.40) MAPTSMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL15960477 0.92 TNKS (0.37) MAPTSMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL15960491 0.91 GABRP (0.39) MAPTSMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL280347 0.91 KDM4E (0.43) MAPTSMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL29589408 0.91 KDM4E (0.43) MAPTSMN1; SMN2NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9923141-B2 Carbazole-based polymer and organic electroluminescence element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-03-20 — — US disclosed
US-9917273-B2 Cross-linking polymer and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-03-13 — — US disclosed
US-8895966-B2 Material for organic electroluminescence element, and organic electroluminescence element using same IDEMITSU KOSAN CO., LTD. (JP) 2014-11-25 — — US disclosed
US-8895966-B2 Material for organic electroluminescence element, and organic electroluminescence element using same IDEMITSU KOSAN CO., LTD. (JP) 2014-11-25 — — US disclosed
US-20140299855-A1 CARBAZOLE-BASED POLYMER AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2014-10-09 — — US disclosed
EP-2770006-A1 CROSS-LINKING POLYMER AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME Idemitsu Kosan Co., Ltd (JP) 2014-08-27 — — EP disclosed
US-20140231771-A1 CROSS-LINKING POLYMER AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. 2014-08-21 — — US disclosed
US-20140231771-A1 CROSS-LINKING POLYMER AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. 2014-08-21 — — US disclosed
US-20130092905-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-04-18 — — US disclosed
US-20130092905-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-04-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130092905-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME LEF1, ORMDL3, CD99 MAPT 932/4885SMN1; SMN2 4200/4885NPC1 3881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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