Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 2/20 | 0.39 |
| ▸ | GABRP | O00591 | 3/20 | 0.38 |
| ▸ | GABRD | O14764 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.38 |
| ▸ | GABRE | P78334 | 3/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12159648 | 0.97 | SMN1; SMN2 (0.41) | KDM4EATML3MBTL1TSPOGABRP | |
| SCHEMBL30445626 | 0.97 | SMN1; SMN2 (0.41) | KDM4EATML3MBTL1TSPOGABRP | |
| SCHEMBL29589408 | 0.97 | KDM4E (0.43) | KDM4EATML3MBTL1TSPOGABRP | |
| SCHEMBL280347 | 0.97 | KDM4E (0.43) | KDM4EATML3MBTL1TSPOGABRP | |
| SCHEMBL14039066 | 0.94 | KDM4E (0.41) | KDM4EATML3MBTL1TSPOGABRP | |
| SCHEMBL14868196 | 0.94 | MAPT (0.42) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL14039041 | 0.93 | KDM4E (0.40) | KDM4EATML3MBTL1TSPOGABRP | |
| SCHEMBL13471423 | 0.92 | PIM1 (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14868195 | 0.92 | PIM1 (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15960477 | 0.92 | TNKS (0.37) | KDM4EATML3MBTL1TSPOGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10431750-B2 | 4H-imidazo[1,2-a]imidazoles for electronic applications | UDC IRELAND LIMITED (IE) | 2019-10-01 | — | — | US | disclosed |
| US-20190273211-A1 | 4H-Imidazo[1,2-a]imidazoles for Electronic Applications | UDC IRELAND LTD (IE) | 2019-09-05 | — | — | US | disclosed |
| EP-3072943-B1 | DIBENZOFURAN/CARBAZOLE-SUBSTITUTED BENZONITRILES | IDEMITSU KOSAN CO (JP) | 2018-05-02 | — | — | EP | disclosed |
| US-9806270-B2 | 4H-imidazo[1,2-a]imidazoles for electronic applications | UDC IRELAND LIMITED (IE) | 2017-10-31 | — | — | US | disclosed |
| US-9806270-B2 | 4H-imidazo[1,2-a]imidazoles for electronic applications | UDC IRELAND LIMITED (IE) | 2017-10-31 | — | — | US | disclosed |
| EP-3072943-A1 | DIBENZOFURAN/CARBAZOLE-SUBSTITUTED BENZONITRILES | Idemitsu Kosan Co., Ltd. (JP) | 2016-09-28 | — | — | EP | disclosed |
| EP-3072943-A1 | DIBENZOFURAN/CARBAZOLE-SUBSTITUTED BENZONITRILES | Idemitsu Kosan Co., Ltd. (JP) | 2016-09-28 | — | — | EP | disclosed |
| US-20160190480-A1 | 4H-Imidazo[1,2-a]imidazoles for Electronic Applications | BASF SE (DE) | 2016-06-30 | — | — | US | disclosed |
| US-20160190480-A1 | 4H-Imidazo[1,2-a]imidazoles for Electronic Applications | BASF SE (DE) | 2016-06-30 | — | — | US | disclosed |
| EP-3034508-A1 | 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS | BASF SE (DE) | 2016-06-22 | — | — | EP | disclosed |
| EP-2688889-B1 | 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS | BASF SE (DE) | 2016-05-18 | — | — | EP | disclosed |
| WO-2012130709-A1 | 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS | BASF SE (DE) | 2012-10-04 | — | — | WO | disclosed |
| US-20120241681-A1 | 4H-Imidazo[1,2-a]imidazoles for Electronic Applications | BASF SE (DE) | 2012-09-27 | — | — | US | disclosed |
| US-20120241681-A1 | 4H-Imidazo[1,2-a]imidazoles for Electronic Applications | BASF SE (DE) | 2012-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120241681-A1 | 4H-Imidazo[1,2-a]imidazoles for Electronic Applications | EIF4A1, ITPR2, ITPR1 | KDM4E 1166/4885ATM 3638/4885L3MBTL1 4368/4885 |
| US-10431750-B2 | 4H-imidazo[1,2-a]imidazoles for electronic applications | EIF4A1, ITPR2, ITPR1 | KDM4E 1166/4885ATM 3638/4885L3MBTL1 4368/4885 |
| US-20190273211-A1 | 4H-Imidazo[1,2-a]imidazoles for Electronic Applications | PAH, NISCH, KCNH1 | KDM4E 1128/4885ATM 3506/4885L3MBTL1 4627/4885 |
| US-20160190480-A1 | 4H-Imidazo[1,2-a]imidazoles for Electronic Applications | PAH, NISCH, KCNH1 | KDM4E 1128/4885ATM 3506/4885L3MBTL1 4627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.