Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | FABP4 | P15090 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 4/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2787546 | 0.87 | MAPT (0.56) | KDM4ENPY5RPOLBALDH1A1HPGD | |
| SCHEMBL17786579 | 0.78 | NPC1 (0.49) | POLBALDH1A1TAS2R14FABP4MEN1 | |
| SCHEMBL783331 | 0.78 | MAPT (0.57) | KDM4EPOLBALDH1A1HPGDSRC | |
| SCHEMBL17589299 | 0.76 | KDM4E (0.46) | KDM4ENPY5RPOLBALDH1A1MEN1 | |
| SCHEMBL17117440 | 0.75 | NPY5R (0.67) | KDM4ENPY5RALDH1A1EGFRSRC | |
| SCHEMBL17786597 | 0.75 | TTR (0.49) | ALDH1A1TAS2R14FABP4MEN1MAPK1 | |
| SCHEMBL18109767 | 0.74 | FABP4 (0.85) | ALDH1A1TAS2R14FABP4MEN1MAPT | |
| SCHEMBL4327511 | 0.74 | NPC1 (0.54) | ALDH1A1HPGDTAS2R14FABP4MAPT | |
| SCHEMBL4727925 | 0.74 | NPY5R (0.65) | KDM4ENPY5RALDH1A1HPGDMEN1 | |
| SCHEMBL14124824 | 0.74 | KDM4E (0.73) | KDM4EPOLBALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130092879-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2013-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130092879-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | CYP1B1, CYP2C19, CYP1A1 | KDM4E 3178/4885NPY5R 2638/4885POLB 1137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.