Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16416922 | 0.82 | CDC7 (0.51) | NPC1ALDH1A1MAPTHPGDALOX12 | |
| SCHEMBL29580587 | 0.79 | CDC7 (0.57) | NPC1ALDH1A1MAPTHPGDALOX12 | |
| SCHEMBL30615425 | 0.77 | MAPK1 (0.50) | NPC1ALDH1A1MAPTHPGDALOX12 | |
| SCHEMBL17786579 | 0.76 | NPC1 (0.49) | NPC1ALDH1A1MAPTRAB9ATAS2R14 | |
| SCHEMBL16686040 | 0.76 | NPC1 (0.63) | NPC1ALDH1A1MAPTHPGDALOX12 | |
| SCHEMBL31378486 | 0.75 | TRPA1 (0.59) | NPC1ALDH1A1MAPTHPGDALOX12 | |
| SCHEMBL29510910 | 0.75 | NPC1 (0.78) | NPC1ALDH1A1MAPTHPGDALOX12 | |
| SCHEMBL10144151 | 0.75 | FABP4 (0.62) | NPC1ALDH1A1MAPTHPGDTAS2R14 | |
| SCHEMBL14870530 | 0.74 | KDM4E (0.56) | ALDH1A1MAPTHPGDTAS2R14FABP4 | |
| SCHEMBL25169245 | 0.74 | NPC1 (0.43) | NPC1ALDH1A1MAPTHPGDALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2039685-A2 | Heterobicyclic compounds as P38 inhibitors | Array Biopharma, Inc. (US) | 2009-03-25 | — | — | EP | claimed |