Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23416843 | 0.85 | KDM4E (0.44) | KDM4EATMNPSR1TDP1MEN1 | |
| SCHEMBL5380250 | 0.84 | KDM4E (0.56) | KDM4EATMNPSR1TDP1LTA4H | |
| SCHEMBL6547955 | 0.83 | TSHR (0.42) | KDM4EATMNPSR1TDP1MEN1 | |
| SCHEMBL20882009 | 0.80 | IDO1 (0.44) | KDM4EATMNPSR1TDP1MEN1 | |
| SCHEMBL9403954 | 0.80 | SLC6A2 (0.47) | TDP1IDO1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10786732 | 0.79 | HDAC1 (0.50) | KDM4EATMTDP1LTA4HIDO1 | |
| SCHEMBL6378299 | 0.76 | POLB (0.51) | MEN1KMT2ALTA4HIDO1CYP3A4 | |
| SCHEMBL2140027 | 0.76 | HTR2A (0.54) | TDP1LTA4HCYP3A4CYP2D6CYP2C19 | |
| SCHEMBL5000663 | 0.75 | POLB (0.44) | NPSR1TDP1MEN1KMT2AIDO1 | |
| SCHEMBL28534680 | 0.75 | IDO1 (0.43) | NPSR1TDP1MEN1KMT2AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140303333-A1 | IRON BISPHENOLATE COMPLEXES AND METHODS OF USE AND SYNTHESIS THEREOF | UNIV PRINCE EDWARD ISLAND (CA) | 2014-10-09 | — | — | US | disclosed |
| US-20140303333-A1 | IRON BISPHENOLATE COMPLEXES AND METHODS OF USE AND SYNTHESIS THEREOF | UNIV PRINCE EDWARD ISLAND (CA) | 2014-10-09 | — | — | US | disclosed |
| WO-2013053046-A1 | IRON BISPHENOLATE COMPLEXES AND METHODS OF USE AND SYNTHESIS THEREOF | UNIVERSITY OF PRINCE EDWARD ISLAND (CA) | 2013-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303333-A1 | IRON BISPHENOLATE COMPLEXES AND METHODS OF USE AND SYNTHESIS THEREOF | TFRC, PCBP1, FECH | KDM4E 1992/4885ATM 3816/4885NPSR1 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.