SCHEMBL6378299

SCHEMBL6378299

Cc1ccc(Cc2ccccc2C)cc1

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.51
LTA4H P09960 1/20 0.49
TAAR1 Q96RJ0 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
TSHR P16473 2/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C19 P33261 1/20 0.45
KEAP1 Q14145 1/20 0.43
IDO1 P14902 1/20 0.42
FFAR1 O14842 1/20 0.42
ACHE P22303 1/20 0.41
SLC5A2 P31639 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8095627 0.93 LTA4H (0.53) POLBLTA4HTAAR1TSHRKEAP1
SCHEMBL9403954 0.90 SLC6A2 (0.47) POLBTAAR1TSHRCYP3A4CYP2D6
Diethylamine SCHEMBL11130316 0.88 POLB (0.44) POLBLTA4HTAAR1MEN1KMT2A
SCHEMBL22240445 0.87 POLB (0.43) POLBLTA4HTSHRCYP3A4CYP2D6
SCHEMBL2140995 0.86 CALM1 (0.57) LTA4HTAAR1MEN1KMT2ATSHR
SCHEMBL2140027 0.86 HTR2A (0.54) POLBLTA4HTSHRCYP3A4CYP2D6
SCHEMBL275838 0.85 CALM1 (0.55) LTA4HTAAR1MEN1KMT2ATSHR
SCHEMBL9741301 0.85 CALM1 (0.55) LTA4HTAAR1MEN1KMT2ATSHR
SCHEMBL29940610 0.85 CALM1 (0.55) LTA4HTAAR1MEN1KMT2ATSHR
Hydrochloric Acid SCHEMBL21175607 0.83 CALM1 (0.52) LTA4HTAAR1MEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11208523-B2 Polycarbodiimide compound and thermosetting resin composition NISSHTNBO CHEMICAL INC. (JP) 2021-12-28 US disclosed
US-20200181314-A1 POLYCARBODIIMIDE COMPOUND AND THERMOSETTING RESIN COMPOSITION NISSHINBO CHEMICAL INC. (JP) 2020-06-11 US disclosed
EP-2258356-B1 CHEMICAL COMPOUNDS HAVING ANTIVIRAL ACTIVITY AGAINST DENGUE VIRUS AND OTHER FLAVIVIRUSES CT INGENIERIA GENETICA BIOTECNOLOGIA (CU) 2017-09-27 EP disclosed
CN-106478326-A The synthetic method of one class diarylmethanes 北京大学 2017-03-08 CN disclosed
US-20150004484-A1 ORGANIC ELECTROLYTE AND ORGANIC ELECTROLYTE STORAGE BATTERY JX NIPPON OIL & ENERGY CORPORATION (JP) 2015-01-01 US disclosed
EP-2797154-A1 ORGANIC ELECTROLYTE, AND ORGANIC ELECTROLYTE STORAGE BATTERY JX Nippon Oil & Energy Corporation (JP) 2014-10-29 EP disclosed
EP-2797153-A1 ORGANIC ELECTROLYTE, AND ORGANIC ELECTROLYTE STORAGE BATTERY JX Nippon Oil & Energy Corporation (JP) 2014-10-29 EP disclosed
CN-103214341-A Method for synthesizing diarylmethane and triarylmethane in one step by using aromatic hydrocarbon and benzyl halid UNIV CHONGQING 2013-07-24 CN disclosed
US-20050227863-A1 Process for aryl-aryl carbon to carbon bond formation by arylation of aryl halide or an aromatic compound COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH 2005-10-13 US disclosed
US-6548722-B1 Liquid-phase alkylation or acylation using hydrotalcite-type catalyst; for chemical intermediates for dyes and drugs COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-04-15 US disclosed
US-6525226-B2 Catalyzing the liquid-phase alkylation or acylation using a hydrotalcite-type catalyst COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-02-25 US disclosed
US-20030018219-A1 PROCESS FOR PREPARATION OF SUBSTITUTED AROMATIC COMPOUND EMPLOYING FRIEDEL-CRAFTS REACTION USING A REUSABLE BASIC ANIONIC CLAY CATALYST CHOUDHARY VASANT RAM CHANDRA (IN) 2003-01-23 US disclosed
US-6215035-B1 LIQUID PHASE REACTION USING SOLID GALLIUM CATALYST COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2001-04-10 US disclosed
US-6180557-B1 INDIUM OR THALLIUM MIXED OXIDE COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2001-01-30 US disclosed
US-4329529-A Traction fluids for traction drive transmissions NIPPON OIL CO., LTD. (JP) 1982-05-11 US disclosed
US-4228023-A Paraffinic insulating oils containing a diarylalkane GULF RESEARCH & DEVELOPMENT COMPANY (US) 1980-10-14 US disclosed