Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.81 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.62 |
| ▸ | F3 | P13726 | 3/20 | 0.60 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | OXTR | P30559 | 1/20 | 0.60 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.60 |
| ▸ | CD81 | P60033 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.55 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.55 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.55 |
| ▸ | PTPRC | P08575 | 2/20 | 0.55 |
| ▸ | PTPRF | P10586 | 2/20 | 0.55 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Barringtogenol C SCHEMBL15132635 | 1.00 | PTPN1 (0.81) | PTPN1AKR1B10AKR1B1ALOX5F3 | |
| Barringtogenol C SCHEMBL1049164 | 1.00 | PTPN1 (0.81) | PTPN1AKR1B10AKR1B1ALOX5F3 | |
| SCHEMBL15883013 | 0.92 | PTPN1 (0.79) | PTPN1AKR1B10AKR1B1ALOX5F3 | |
| SCHEMBL19360132 | 0.92 | PTPN1 (0.79) | PTPN1AKR1B10AKR1B1ALOX5F3 | |
| SCHEMBL4324523 | 0.91 | PTPN1 (0.68) | PTPN1AKR1B10AKR1B1ALOX5F3 | |
| SCHEMBL15132632 | 0.91 | PTPN1 (0.68) | PTPN1AKR1B10AKR1B1ALOX5F3 | |
| SCHEMBL30222071 | 0.91 | PTPN1 (0.68) | PTPN1AKR1B10AKR1B1ALOX5F3 | |
| SCHEMBL1050527 | 0.91 | PTPN1 (0.68) | PTPN1AKR1B10AKR1B1ALOX5F3 | |
| SCHEMBL19284333 | 0.90 | PTPN1 (1.00) | PTPN1AKR1B10AKR1B1ALOX5F3 | |
| SCHEMBL29934333 | 0.90 | PTPN1 (1.00) | PTPN1AKR1B10AKR1B1ALOX5F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013055244-A1 | PREPARATION OF PROTOESCIGENIN FROM ESCIN | INSTYTUT FARMACEUTYCZNY (PL) | 2013-04-18 | — | — | WO | disclosed |