Barringtogenol C

Barringtogenol C

SCHEMBL1049164

CC1(C)C[C@H]2C3=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]4(C)[C@]3(C)C[C@@H](O)[C@@]2(CO)[C@@H](O)[C@@H]1O

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 9/20 0.81
▸ AKR1B10 O60218 3/20 0.63
▸ AKR1B1 P15121 1/20 0.63
▸ ALOX5 P09917 1/20 0.62
▸ F3 P13726 3/20 0.60
▸ SIRT5 Q9NXA8 3/20 0.60
▸ CYP3A4 P08684 1/20 0.60
▸ MAPK1 P28482 1/20 0.60
▸ OXTR P30559 1/20 0.60
▸ AVPR1A P37288 1/20 0.60
▸ CD81 P60033 1/20 0.60
▸ USP2 O75604 2/20 0.59
▸ POLB P06746 3/20 0.55
▸ PTPN2 P17706 3/20 0.55
▸ PSMB11 A5LHX3 2/20 0.55
▸ PSMA7 O14818 2/20 0.55
▸ PLA2G1B P04054 2/20 0.55
▸ PTPRC P08575 2/20 0.55
▸ PTPRF P10586 2/20 0.55
▸ PSMB1 P20618 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Barringtogenol C SCHEMBL15132635 1.00 PTPN1 (0.81) PTPN1AKR1B10AKR1B1ALOX5F3
Barringtogenol C SCHEMBL14871943 1.00 PTPN1 (0.81) PTPN1AKR1B10AKR1B1ALOX5F3
SCHEMBL15883013 0.92 PTPN1 (0.79) PTPN1AKR1B10AKR1B1ALOX5F3
SCHEMBL19360132 0.92 PTPN1 (0.79) PTPN1AKR1B10AKR1B1ALOX5F3
SCHEMBL4324523 0.91 PTPN1 (0.68) PTPN1AKR1B10AKR1B1ALOX5F3
SCHEMBL15132632 0.91 PTPN1 (0.68) PTPN1AKR1B10AKR1B1ALOX5F3
SCHEMBL30222071 0.91 PTPN1 (0.68) PTPN1AKR1B10AKR1B1ALOX5F3
SCHEMBL1050527 0.91 PTPN1 (0.68) PTPN1AKR1B10AKR1B1ALOX5F3
SCHEMBL19284333 0.90 PTPN1 (1.00) PTPN1AKR1B10AKR1B1ALOX5F3
SCHEMBL29934333 0.90 PTPN1 (1.00) PTPN1AKR1B10AKR1B1ALOX5F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4674894-A2 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES Hemoteq AG (DE) 2026-01-07 — — EP claimed
EP-4663688-A2 CROSSLINKERS Hemoteq AG (DE) 2025-12-17 — — EP claimed
US-20250295800-A1 CONJUGATE OF A SINGLE DOMAIN ANTIBODY, A SAPONIN AND AN EFFECTOR MOLECULE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, THERAPEUTIC USE OF SAID PHARMACEUTICAL COMPOSITION SAPREME TECH BV (NL) 2025-09-25 — — US claimed
EP-4610278-A2 TARGETED SAPONIN-NUCLEIC ACID CONJUGATES FOR TREATMENT OF MUSCLE WASTING DISORDERS Sapreme Technologies B.V. (NL) 2025-09-03 — — EP claimed
EP-4596052-A2 THERAPEUTIC COMBINATION OF GALNAC-OLIGONUCLEOTIDE CONJUGATE AND SAPONIN, AND USES THEREOF Sapreme Technologies B.V. (NL) 2025-08-06 — — EP claimed
EP-4452331-B1 TARGETED SAPONIN-NUCLEIC ACID CONJUGATES FOR TREATMENT OF MUSCLE WASTING DISORDERS SAPREME TECH BV (NL) 2025-08-06 — — EP claimed
EP-4591938-A2 CONJUGATE OF SAPONIN, OLIGONUCLEOTIDE AND GALNAC Sapreme Technologies B.V. (NL) 2025-07-30 — — EP claimed
EP-4210760-B1 CONJUGATE OF SAPONIN, OLIGONUCLEOTIDE AND GALNAC SAPREME TECH BV (NL) 2025-06-18 — — EP claimed
EP-4529953-A2 CONJUGATE OF SAPONIN, OLIGONUCLEOTIDE AND GALNAC Sapreme Technologies B.V. (NL) 2025-04-02 — — EP claimed
US-20250082759-A1 COMPOSITIONS COMPRISING THERAPEUTIC NUCLEIC ACID AND TARGETED SAPONIN FOR THE TREATMENT OF MUSCLE-WASTING DISORDERS SAPREME TECHNOLOGIES B.V. (NL) 2025-03-13 — — US claimed
CN-103509077-A Triterpene saponin compound, its preparation method and applications UNIV SHENYANG PHARMACEUTICAL 2014-01-15 — — CN claimed
US-20130190538-A1 PROCESS FOR THE PREPARATION OF PROTOESCIGENIN WARSZAWSKI UNIWERSYTET MEDYCZNY (PL) 2013-07-25 — — US claimed
WO-2013055244-A1 PREPARATION OF PROTOESCIGENIN FROM ESCIN INSTYTUT FARMACEUTYCZNY (PL) 2013-04-18 — — WO claimed
JP-4790620-B2 — — 2011-10-12 — — JP claimed
US-7618946-B2 Analgesic compounds, extracts containing same and methods of preparation GRIFFITH UNIVERSITY (AU) 2009-11-17 — — US claimed
US-20070270375-A1 Novel Analgesic Compounds, Extracts Containing Same and Methods of Preparation JARLMADANGAH BURU ABORIGINAL CORPORATION (AU) 2007-11-22 — — US claimed
CN-1938326-A Novel analgesic compounds, extracts containing same and methods of preparation UNIV GRIFFITH (AU) 2007-03-28 — — CN claimed
EP-1687320-A1 NOVEL ANALGESIC COMPOUNDS, EXTRACTS CONTAINING SAME AND METHODS OF PREPARATION GRIFFITH UNIVERSITY (AU) 2006-08-09 — — EP claimed
WO-2005051969-A1 NOVEL ANALGESIC COMPOUNDS, EXTRACTS CONTAINING SAME AND METHODS OF PREPARATION GRIFFITH UNIVERSITY (AU) 2005-06-09 — — WO claimed
CN-1568166-A Coated stent for preventing restenosis HEMOTEQ GMBH (DE) 2005-01-19 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130190538-A1 PROCESS FOR THE PREPARATION OF PROTOESCIGENIN PSAP, SEPTIN6, ESPL1 PTPN1 3275/4885AKR1B10 1055/4885AKR1B1 2181/4885
US-20250295800-A1 CONJUGATE OF A SINGLE DOMAIN ANTIBODY, A SAPONIN AND AN EFFECTOR MOLECULE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, THERAPEUTIC USE OF SAID PHARMACEUTICAL COMPOSITION CYP46A1, HCCS, DHCR7 PTPN1 485/4885AKR1B10 54/4885AKR1B1 59/4885
US-20250082759-A1 COMPOSITIONS COMPRISING THERAPEUTIC NUCLEIC ACID AND TARGETED SAPONIN FOR THE TREATMENT OF MUSCLE-WASTING DISORDERS MUSK, TNNC1, PYGM PTPN1 2705/4885AKR1B10 3160/4885AKR1B1 2634/4885
US-20070270375-A1 Novel Analgesic Compounds, Extracts Containing Same and Methods of Preparation DDOST, BBOX1, DAD1 PTPN1 4182/4885AKR1B10 958/4885AKR1B1 1887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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