Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16022757 | 0.88 | LMNA (0.55) | LMNASMN1; SMN2GAAL3MBTL1NPC1 | |
| SCHEMBL28380448 | 0.81 | TDP1 (0.54) | SMN1; SMN2GAAL3MBTL1NPC1RAB9A | |
| SCHEMBL22504147 | 0.81 | LMNA (0.61) | LMNASMN1; SMN2GAAL3MBTL1NPC1 | |
| SCHEMBL27375098 | 0.81 | TDP1 (0.59) | LMNASMN1; SMN2GAAL3MBTL1THRB | |
| SCHEMBL14872195 | 0.78 | NPC1 (0.61) | LMNASMN1; SMN2GAAL3MBTL1THRB | |
| SCHEMBL4457246 | 0.76 | LMNA (0.66) | LMNASMN1; SMN2GAAL3MBTL1NPC1 | |
| SCHEMBL27374907 | 0.76 | TDP1 (0.52) | LMNASMN1; SMN2GAAL3MBTL1THRB | |
| SCHEMBL27374991 | 0.76 | HPGD (0.62) | LMNASMN1; SMN2GAAL3MBTL1THRB | |
| SCHEMBL27522659 | 0.75 | TDP1 (0.64) | SMN1; SMN2GAAL3MBTL1THRBHPGD | |
| SCHEMBL27828214 | 0.75 | LMNA (0.57) | LMNASMN1; SMN2GAAL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11465960-B2 | Labile esters of agrochemicals for controlled release and reduction of off-site movement | MONSANTO TECHNOLOGY LLC (US) | 2022-10-11 | — | — | US | disclosed |
| US-20200392063-A1 | LABILE ESTERS OF AGROCHEMICALS FOR CONTROLLED RELEASE AND REDUCTION OF OFF-SITE MOVEMENT | MONSANTO TECHNOLOGY LLC (US) | 2020-12-17 | — | — | US | disclosed |
| US-20170029355-A1 | LABILE ESTERS OF AGROCHEMICALS FOR CONTROLLED RELEASE AND REDUCTION OF OFF-SITE MOVEMENT | MONSANTO TECHNOLOGY LLC | 2017-02-02 | — | — | US | disclosed |
| US-20170029355-A1 | LABILE ESTERS OF AGROCHEMICALS FOR CONTROLLED RELEASE AND REDUCTION OF OFF-SITE MOVEMENT | MONSANTO TECHNOLOGY LLC | 2017-02-02 | — | — | US | disclosed |
| US-20140256549-A1 | LABILE ESTERS OF AGROCHEMICALS FOR CONTROLLED RELEASE AND REDUCTION OF OFF-SITE MOVEMENT | MONSANTO TECHNOLOGY LLC (US) | 2014-09-11 | — | — | US | disclosed |
| WO-2013055944-A2 | LABILE ESTERS OF AGROCHEMICALS FOR CONTROLLED RELEASE AND REDUCTION OF OFF-SITE MOVEMENT | MONSANTO TECHNOLOGY LLC (US) | 2013-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11465960-B2 | Labile esters of agrochemicals for controlled release and reduction of off-site movement | APEH, GUSB, CES2 | LMNA 2263/4885SMN1; SMN2 3744/4885GAA 12/4885 |
| US-20200392063-A1 | LABILE ESTERS OF AGROCHEMICALS FOR CONTROLLED RELEASE AND REDUCTION OF OFF-SITE MOVEMENT | APEH, GUSB, CES2 | LMNA 2263/4885SMN1; SMN2 3744/4885GAA 12/4885 |
| US-20170029355-A1 | LABILE ESTERS OF AGROCHEMICALS FOR CONTROLLED RELEASE AND REDUCTION OF OFF-SITE MOVEMENT | APEH, GUSB, CES2 | LMNA 2263/4885SMN1; SMN2 3744/4885GAA 12/4885 |
| US-20140256549-A1 | LABILE ESTERS OF AGROCHEMICALS FOR CONTROLLED RELEASE AND REDUCTION OF OFF-SITE MOVEMENT | APEH, GUSB, CES2 | LMNA 2263/4885SMN1; SMN2 3744/4885GAA 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.