Glutamic Acid

Glutamic Acid

SCHEMBL148727

N[C@@H](CCC(=O)O)C(=O)O.O=C(O)CCC(=O)C(=O)O

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 2/20 0.75
GRM6 O15303 2/20 0.75
GRM7 Q14831 2/20 0.75
GRM4 Q14833 2/20 0.75
GSR P00390 2/20 0.75
GRIN2D O15399 1/20 0.75
GRIN3B O60391 1/20 0.75
CYP1A2 P05177 1/20 0.75
GRIK1 P39086 1/20 0.75
GRM5 P41594 1/20 0.75
GRIA1 P42261 1/20 0.75
GRIA2 P42262 1/20 0.75
GRIA3 P42263 1/20 0.75
SLC1A3 P43003 1/20 0.75
SLC1A2 P43004 1/20 0.75
SLC1A1 P43005 1/20 0.75
GRIA4 P48058 1/20 0.75
GRIN1 Q05586 1/20 0.75
GRIN2A Q12879 1/20 0.75
GRIK2 Q13002 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
D-Glutamate SCHEMBL6138602 1.00 GRM8 (0.75) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL148726 1.00 GRM8 (0.75) GRM8GRM6GRM7GRM4GSR
Glutamine SCHEMBL1033431 0.90 ALOX15 (0.70) GRM8GRM6GRM7GRM4GSR
Glutamine SCHEMBL1033433 0.90 ALOX15 (0.70) GRM8GRM6GRM7GRM4GSR
Alpha-Ketoglutaric Acid SCHEMBL20857029 0.90 GSR (0.59) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL4234844 0.89 GSR (0.60) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL4234847 0.89 GSR (0.60) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL7294273 0.89 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL7294270 0.89 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL31507089 0.89 GRM8 (0.95) GRM8GRM6GRM7GRM4GSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1968372-B1 Promoter sequence obtained from rice and methods of use ARCADIA BIOSCIENCES INC (US) 2012-02-08 EP claimed
US-6864405-B1 Transgenic plants that exhibit enhanced nitrogen assimilation NEW YORK UNIVERSITY (US) 2005-03-08 US claimed
US-20020069430-A1 Transgenic plants that exhibit enhanced nitrogen assimilation AJINOMOTO CO., INC. (JP) 2002-06-06 US claimed
EP-0722494-A4 TRANSGENIC PLANTS THAT EXHIBIT ENHANCED NITROGEN ASSIMILATION UNIV NEW YORK (US) 1999-06-23 EP claimed
EP-0722494-A1 TRANSGENIC PLANTS THAT EXHIBIT ENHANCED NITROGEN ASSIMILATION NEW YORK UNIVERSITY (US) 1996-07-24 EP claimed
WO-1995009911-A1 TRANSGENIC PLANTS THAT EXHIBIT ENHANCED NITROGEN ASSIMILATION NEW YORK UNIVERSITY (US) 1995-04-13 WO claimed
EP-3952644-B1 METHOD AND APPARATUS FOR RECONDITIONING KIDNEYS UGLK SCIENCE AB (SE) 2025-09-24 EP disclosed
US-20240124884-A1 METHODS AND COMPOSITIONS FOR USE OF DIRECTED RECOMBINATION IN PLANT BREEDING MONSANTO TECHNOLOGY LLC (US) 2024-04-18 US disclosed
CN-109476600-B Pyridinethione, pharmaceutical compositions thereof and therapeutic use thereof for the treatment of proliferative, inflammatory, neurodegenerative or immune-mediated diseases 纽罗赛里克斯加拿大有限公司 2023-06-23 CN disclosed
US-20220183272-A1 METHOD AND APPARATUS FOR RECONDITIONING ORGANS UGLX RESEARCH AB (SE) 2022-06-16 US disclosed
US-20220183273-A1 METHOD AND APPARATUS FOR RECONDITIONING KIDNEYS UGLK SCIENCE AB (SE) 2022-06-16 US disclosed
US-10435698-B2 Methods and vectors for producing transgenic plants Monosanto Technology LLC (US) 2019-10-08 US disclosed
US-20190150383-A1 METHODS FOR HYBRID CORN SEED PRODUCTION AND COMPOSITIONS PRODUCED THEREFROM MONSANTO TECHNOLOGY LLC (US) 2019-05-23 US disclosed
EP-0981600-A1 TRANSFORMED MICROORGANISMS WITH IMPROVED PROPERTIES VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) 2000-03-01 EP disclosed
US-5955651-A Transgenic plants that exhibit enhanced nitrogen assimilation NEW YORK UNIVERSITY (US) 1999-09-21 US disclosed
WO-1999046363-A1 TRANSFORMED MICROORGANISMS WITH IMPROVED PROPERTIES VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) 1999-09-16 WO disclosed
EP-0722494-A4 TRANSGENIC PLANTS THAT EXHIBIT ENHANCED NITROGEN ASSIMILATION UNIV NEW YORK (US) 1999-06-23 EP disclosed
EP-0722494-A1 TRANSGENIC PLANTS THAT EXHIBIT ENHANCED NITROGEN ASSIMILATION NEW YORK UNIVERSITY (US) 1996-07-24 EP disclosed
WO-1995009911-A1 TRANSGENIC PLANTS THAT EXHIBIT ENHANCED NITROGEN ASSIMILATION NEW YORK UNIVERSITY (US) 1995-04-13 WO disclosed
EP-0097949-A2 L-glutamic acid oxidase, its production, and its use Yamasa Shoyu Kabushiki Kaisha (JP) 1984-01-11 EP disclosed