Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.59 |
| ▸ | GRM8 | O00222 | 2/20 | 0.59 |
| ▸ | GRM6 | O15303 | 2/20 | 0.59 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.59 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.59 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.59 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.59 |
| ▸ | GRM5 | P41594 | 1/20 | 0.59 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.59 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.59 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.59 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.59 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.59 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.59 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.59 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.59 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.59 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (S)-2-Aminoadipic Acid SCHEMBL1470353 | 0.94 | GSR (0.57) | GSRGRM8GRM6GRM7GRM4 | |
| Alpha-Ketoglutaric Acid SCHEMBL393521 | 0.91 | GSR (0.60) | GSRGRM8GRM6GRM7GRM4 | |
| Alpha-Ketoglutaric Acid SCHEMBL393522 | 0.91 | GSR (0.60) | GSRGRM8GRM6GRM7GRM4 | |
| D-Glutamate SCHEMBL6138602 | 0.90 | GRM8 (0.75) | GSRGRM8GRM6GRM7GRM4 | |
| Glutamic Acid SCHEMBL148727 | 0.90 | GRM8 (0.75) | GSRGRM8GRM6GRM7GRM4 | |
| D-Glutamate SCHEMBL148726 | 0.90 | GRM8 (0.75) | GSRGRM8GRM6GRM7GRM4 | |
| Lysine SCHEMBL3457784 | 0.89 | GSR (0.69) | GSRGRM8GRM6GRM7GRM4 | |
| Lysine SCHEMBL1442876 | 0.89 | GSR (0.69) | GSRGRM8GRM6GRM7GRM4 | |
| D-Glutamate SCHEMBL4234844 | 0.88 | GSR (0.60) | GSRGRM8GRM6GRM7GRM4 | |
| Glutamic Acid SCHEMBL4234847 | 0.88 | GSR (0.60) | GSRGRM8GRM6GRM7GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3688169-A2 | GENETIC KNOCKOUTS IN WOOD-LJUNGDAHL MICROORGANISMS | Lanzatech, Inc. (US) | 2020-08-05 | — | — | EP | disclosed |
| US-20200239896-A1 | GENETIC KNOCKOUTS IN WOOD-LJUNGDAHL MICROORGANISMS | LANZATECH, INC. | 2020-07-30 | — | — | US | disclosed |
| WO-2019068011-A2 | GENETIC KNOCKOUTS IN WOOD-LJUNGDAHL MICROORGANISMS | LANZATECH, INC. (US) | 2019-04-04 | — | — | WO | disclosed |