Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14860959 | 0.86 | MAPT (0.52) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL14860961 | 0.86 | MAPT (0.52) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL14873081 | 0.81 | GPR119 (0.49) | GPR119CHRM2CHRM1CHRM3 | |
| SCHEMBL3372121 | 0.79 | GPR119 (0.58) | GPR119MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14873161 | 0.78 | GPR119 (0.72) | GPR119CHRM2CHRM1CHRM3 | |
| SCHEMBL14873089 | 0.77 | GPR119 (0.48) | GPR119CHRM2CHRM1CHRM3 | |
| SCHEMBL14873077 | 0.76 | GPR119 (0.47) | GPR119CHRM2CHRM1CHRM3 | |
| SCHEMBL14873092 | 0.75 | GPR119 (0.48) | GPR119CHRM2CHRM1CHRM3 | |
| SCHEMBL14873175 | 0.75 | GPR119 (0.48) | GPR119CHRM2CHRM1CHRM3 | |
| SCHEMBL14873080 | 0.74 | GPR119 (0.52) | GPR119CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013055910-A1 | MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2013-04-18 | — | — | WO | disclosed |