Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3373764 | 0.91 | CHEK2 (0.52) | GPR119MAPTCHEK2MEN1KMT2A | |
| SCHEMBL3372317 | 0.88 | GPR119 (0.50) | GPR119MAPTCHEK2MEN1KMT2A | |
| SCHEMBL3370707 | 0.86 | GPR119 (0.50) | GPR119CHEK2SMN1; SMN2 | |
| SCHEMBL904065 | 0.84 | GPR119 (0.52) | GPR119MAPTCHEK2MEN1KMT2A | |
| SCHEMBL3373458 | 0.81 | GPR119 (0.56) | GPR119MAPTCHEK2SMN1; SMN2 | |
| SCHEMBL23410251 | 0.81 | GPR119 (0.67) | GPR119CHEK2 | |
| SCHEMBL4773784 | 0.79 | GPR119 (0.64) | GPR119MAPT | |
| SCHEMBL16989407 | 0.79 | GPR119 (0.74) | GPR119 | |
| SCHEMBL15312743 | 0.79 | GPR119 (0.50) | GPR119 | |
| SCHEMBL14873170 | 0.79 | GPR119 (0.53) | GPR119MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048149-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010048149-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |