SCHEMBL14874529

SCHEMBL14874529

CCOC(=O)C(C)(C)C(c1ccccc1OC)C(C)C

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.42
▸ MEN1 O00255 3/20 0.42
▸ MAPT P10636 2/20 0.42
▸ POLB P06746 2/20 0.42
▸ PLIN1 O60240 1/20 0.42
▸ LMNA P02545 1/20 0.42
▸ PLIN5 Q00G26 1/20 0.42
▸ ABHD5 Q8WTS1 1/20 0.42
▸ MMP8 P22894 1/20 0.41
▸ HTT P42858 1/20 0.40
▸ NPSR1 Q6W5P4 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ GAA P10253 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ PIN1 Q13526 1/20 0.39
▸ CNR2 P34972 2/20 0.39
▸ FBP1 P09467 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14874445 0.87 KMT2A (0.44) KMT2AMEN1MAPTPOLBPLIN1
SCHEMBL14874357 0.86 GAA (0.41) KMT2AMEN1MAPTPOLBPLIN1
SCHEMBL14874612 0.86 MEN1 (0.40) KMT2AMEN1MAPTPOLBPLIN1
SCHEMBL14874573 0.86 MEN1 (0.43) KMT2AMEN1MAPTPOLBPLIN1
SCHEMBL14874468 0.84 MMP8 (0.39) KMT2AMEN1MAPTPOLBPLIN1
SCHEMBL14880184 0.84 GAA (0.40) KMT2AMEN1MAPTPOLBPLIN1
SCHEMBL14874321 0.83 MEN1 (0.39) KMT2AMEN1MAPTPOLBPLIN1
SCHEMBL14874629 0.82 GAA (0.38) KMT2AMEN1MAPTPOLBPLIN1
SCHEMBL14874491 0.82 KDM4E (0.43) KMT2AMEN1MAPTPOLBPLIN1
SCHEMBL14874636 0.81 PIN1 (0.38) KMT2AMEN1MAPTPOLBPLIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2768873-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2017-11-22 — — EP disclosed
CN-104254551-A CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SPA 2014-12-31 — — CN disclosed
US-8921253-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2014-12-30 — — US disclosed
US-20140243490-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia, s.r.l. (IT) 2014-08-28 — — US disclosed
EP-2768873-A2 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2014-08-27 — — EP disclosed
WO-2013057026-A2 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2013-04-25 — — WO disclosed
EP-2583985-A1 Catalyst components for the polymerization of olefins Basell Poliolefine Italia S.r.l. (IT) 2013-04-24 — — EP disclosed
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