Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.43 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14874519 | 0.88 | KMT2A (0.46) | MEN1KMT2AMAPTPOLBPLIN1 | |
| SCHEMBL14874529 | 0.86 | KMT2A (0.42) | MEN1KMT2AMAPTPOLBPLIN1 | |
| SCHEMBL14874612 | 0.84 | MEN1 (0.40) | MEN1KMT2AMAPTPOLBPLIN1 | |
| SCHEMBL14874357 | 0.84 | GAA (0.41) | MEN1KMT2AMAPTPOLBPLIN1 | |
| SCHEMBL14874321 | 0.83 | MEN1 (0.39) | MEN1KMT2AMAPTPOLBPLIN1 | |
| SCHEMBL14874404 | 0.83 | POLB (0.42) | MEN1KMT2AMAPTPOLBPLIN1 | |
| SCHEMBL14874468 | 0.82 | MMP8 (0.39) | MEN1KMT2AMAPTPOLBPLIN1 | |
| SCHEMBL14880184 | 0.82 | GAA (0.40) | MEN1KMT2AMAPTPOLBPLIN1 | |
| SCHEMBL14874636 | 0.81 | PIN1 (0.38) | MEN1KMT2AMAPTPOLBPLIN1 | |
| SCHEMBL14874629 | 0.80 | GAA (0.38) | MEN1KMT2AMAPTPOLBPLIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2768873-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2017-11-22 | — | — | EP | disclosed |
| US-8921253-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2014-12-30 | — | — | US | disclosed |
| US-20140243490-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia, s.r.l. (IT) | 2014-08-28 | — | — | US | disclosed |
| EP-2768873-A2 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2014-08-27 | — | — | EP | disclosed |
| WO-2013057026-A2 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2013-04-25 | — | — | WO | disclosed |
| EP-2583985-A1 | Catalyst components for the polymerization of olefins | Basell Poliolefine Italia S.r.l. (IT) | 2013-04-24 | — | — | EP | disclosed |