SCHEMBL14874572

SCHEMBL14874572

CCOC(=O)C(CC(C)C)(C(C)c1ccccc1OC)C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MMP8 P22894 2/20 0.40
▸ MAPT P10636 3/20 0.39
▸ MEN1 O00255 3/20 0.39
▸ KMT2A Q03164 3/20 0.39
▸ POLB P06746 2/20 0.39
▸ PLIN1 O60240 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ PLIN5 Q00G26 1/20 0.39
▸ ABHD5 Q8WTS1 1/20 0.39
▸ HTT P42858 2/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ KDM4E B2RXH2 1/20 0.38
▸ PIN1 Q13526 1/20 0.37
▸ MTNR1A P48039 1/20 0.36
▸ MTNR1B P49286 1/20 0.36
▸ CNR2 P34972 2/20 0.36
▸ HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14874389 0.90 KMT2A (0.41) MMP8MAPTMEN1KMT2APOLB
SCHEMBL14874629 0.89 GAA (0.38) MMP8MAPTMEN1KMT2APOLB
SCHEMBL14874432 0.88 TSHR (0.39) MMP8MAPTMEN1KMT2APOLB
SCHEMBL14874674 0.86 ITGA4 (0.40) MMP8MAPTMEN1KMT2APOLB
SCHEMBL14874528 0.84 MMP8 (0.41) MMP8MAPTMEN1KMT2APOLB
SCHEMBL14874445 0.84 KMT2A (0.44) MMP8MAPTMEN1KMT2APOLB
SCHEMBL14874356 0.81 GAA (0.44) MMP8MAPTMEN1KMT2APOLB
SCHEMBL14880184 0.81 GAA (0.40) MMP8MAPTMEN1KMT2APOLB
SCHEMBL14874438 0.81 PIN1 (0.40) MMP8MAPTMEN1KMT2APOLB
SCHEMBL14874664 0.80 MMP8 (0.38) MMP8MAPTMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2768873-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2017-11-22 — — EP disclosed
US-8921253-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2014-12-30 — — US disclosed
US-20140243490-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia, s.r.l. (IT) 2014-08-28 — — US disclosed
EP-2768873-A2 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2014-08-27 — — EP disclosed
WO-2013057026-A2 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2013-04-25 — — WO disclosed
EP-2583985-A1 Catalyst components for the polymerization of olefins Basell Poliolefine Italia S.r.l. (IT) 2013-04-24 — — EP disclosed
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