SCHEMBL1487475

SCHEMBL1487475

CC(=O)Nc1ccc(OC=O)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.63
KMT2A Q03164 4/20 0.63
TDP1 Q9NUW8 2/20 0.58
LMNA P02545 1/20 0.58
CYP1A2 P05177 1/20 0.58
SMN1; SMN2 Q16637 4/20 0.55
HTT P42858 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
CA9 Q16790 2/20 0.54
NPSR1 Q6W5P4 1/20 0.54
ALDH1A1 P00352 5/20 0.53
MAPT P10636 4/20 0.53
CA12 O43570 1/20 0.53
BRD4 O60885 1/20 0.53
NR1I2 O75469 1/20 0.53
MB P02144 1/20 0.53
CYP1A1 P04798 1/20 0.53
CA3 P07451 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19193312 0.90 MEN1 (0.53) MEN1KMT2ATDP1LMNACYP1A2
SCHEMBL19193960 0.89 PKM (0.62) MEN1KMT2ALMNASMN1; SMN2HTT
SCHEMBL10701935 0.81 CYP3A4 (0.53) MEN1KMT2ATDP1LMNACYP1A2
SCHEMBL15036513 0.81 LMNA (0.48) MEN1KMT2ATDP1LMNACYP1A2
SCHEMBL15036515 0.81 LMNA (0.48) MEN1KMT2ATDP1LMNACYP1A2
SCHEMBL7348168 0.80 KMT2A (0.53) MEN1KMT2ALMNACYP1A2SMN1; SMN2
SCHEMBL6516221 0.79 KMT2A (0.73) MEN1KMT2ATDP1LMNACYP1A2
SCHEMBL17253347 0.79 KMT2A (0.72) MEN1KMT2ATDP1LMNACYP1A2
SCHEMBL7350331 0.79 MTNR1A (0.55) MEN1KMT2ATDP1CYP1A2SMN1; SMN2
SCHEMBL861674 0.78 SMN1; SMN2 (0.84) MEN1KMT2ATDP1SMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999052936-A2 ARGININE PEPTIDE ANALOGS USEFUL AS FIBROBLAST GROWTH FACTOR ANTAGONISTS EISAI CO., LTD. (JP) 1999-10-21 WO claimed
EP-0100168-B1 PROCESSES FOR PREPARING TABLETS BY A MODIFIED 'WET-GRANULATION' TECHNIQUE Rogerson, Alan George (GB) 1988-12-28 EP claimed
US-4562024-A HOMOGENIZING PART OF SOLID WITH GRANULATING FLUID TO FORM UNIFORM SLURRY, MOISTENING REST OF SOLID WITH SLURRY FORMED STERLING DRUG INC. (US) 1985-12-31 US claimed
EP-0100168-A2 Processes for preparing tablets by a modified 'wet-granulation' technique Rogerson, Alan George (GB) 1984-02-08 EP claimed
WO-2024070633-A1 OPTICAL FILM, POLARIZING PLATE, COMPOSITION FOR FORMING ALIGNMENT FILM, AND METHOD FOR PRODUCING POLARIZING PLATE 富士フイルム株式会社 2024-04-04 WO disclosed
WO-2024070463-A1 POLYMER AND COMPOSITION 富士フイルム株式会社 2024-04-04 WO disclosed
WO-2024070641-A1 OPTICAL FILM, POLARIZING PLATE, COMPOSITION FOR ALIGNMENT FILM FORMATION, AND METHOD FOR PRODUCING POLARIZING PLATE 富士フイルム株式会社 2024-04-04 WO disclosed
WO-2023138681-A1 ACIDIC SALT OR CRYSTAL FORM OF NITROGEN-CONTAINING FUSED RING DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海翰森生物医药科技有限公司 2023-07-27 WO disclosed
US-9067878-B2 Organogel compositions comprising alkylated aromatic acids XEROX CORPORATION (US) 2015-06-30 US disclosed
US-20130158135-A1 Organogel Compositions Comprising Alkylated Aromatic Acids NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2013-06-20 US disclosed
CN-102427813-A Novel anti-inflammatory agents RESVERLOGIX CORP 2012-04-25 CN disclosed
EP-2301519-A1 Ultraviolet absorbing composition Fujifilm Corporation (JP) 2011-03-30 EP disclosed
EP-0276124-A2 Prostaglandin derivatives, their preparation and their therapeutic use Sankyo Company Limited (JP) 1988-07-27 EP disclosed
US-4562024-A HOMOGENIZING PART OF SOLID WITH GRANULATING FLUID TO FORM UNIFORM SLURRY, MOISTENING REST OF SOLID WITH SLURRY FORMED STERLING DRUG INC. (US) 1985-12-31 US disclosed
EP-0100168-A2 Processes for preparing tablets by a modified 'wet-granulation' technique Rogerson, Alan George (GB) 1984-02-08 EP disclosed
US-4367272-A MORDANTS, REFLECTION FUJI PHOTO FILM CO., LTD (JP) 1983-01-04 US disclosed
US-4268621-A Direct positive photographic material KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-05-19 US disclosed
US-4264495-A EXHIBITING GOOD COLOFASTNESS AND DYEABILITY ON POLYAMIDES AND OTHER FIBERS EASTMAN KODAK COMPANY (US) 1981-04-28 US disclosed
US-4247458-A COUPLING DIAZONIUM SALT WITH DISPERSE DYE COUPLER WITH DISPLACEABLE GROUP OTHER THAN HYDROGEN EASTMAN KODAK COMPANY (US) 1981-01-27 US disclosed
US-4070352-A COLORFAST, SUBLIMATION AND OZONE RESISTANT BLUE AZO DYES FOR POLYAMIDES EASTMAN KODAK COMPANY (US) 1978-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130158135-A1 Organogel Compositions Comprising Alkylated Aromatic Acids F12, AHR, RXRG MEN1 3557/4885KMT2A 2571/4885TDP1 1253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.