Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 9/20 | 1.00 |
| ▸ | PNMT | P11086 | 3/20 | 0.68 |
| ▸ | MAOB | P27338 | 3/20 | 0.63 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.58 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.58 |
| ▸ | HTR3B | O95264 | 1/20 | 0.58 |
| ▸ | HTR3A | P46098 | 1/20 | 0.58 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.58 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | DRD1 | P21728 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | AGXT | P21549 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30643998 | 1.00 | TAAR1 (1.00) | TAAR1PNMTMAOBAOC3HTR3E | |
| Iodide SCHEMBL30914654 | 0.98 | TAAR1 (0.96) | TAAR1PNMTMAOBAOC3HTR3E | |
| Hydrochloric Acid SCHEMBL31185455 | 0.98 | TAAR1 (0.96) | TAAR1PNMTMAOBAOC3HTR3E | |
| Hydrochloric Acid SCHEMBL10898373 | 0.98 | TAAR1 (0.96) | TAAR1PNMTMAOBAOC3HTR3E | |
| Bromide SCHEMBL10898852 | 0.98 | TAAR1 (0.96) | TAAR1PNMTMAOBAOC3HTR3E | |
| Hydrochloric Acid SCHEMBL2175082 | 0.98 | TAAR1 (0.96) | TAAR1PNMTMAOBAOC3HTR3E | |
| Hydrochloric Acid SCHEMBL10899915 | 0.96 | TAAR1 (0.92) | TAAR1PNMTMAOBAOC3HTR3E | |
| SCHEMBL2026417 | 0.87 | TAAR1 (0.77) | TAAR1PNMTMAOBAOC3HTR3E | |
| SCHEMBL8356897 | 0.86 | TAAR1 (0.73) | TAAR1PNMTMAOBAOC3HTR3E | |
| SCHEMBL12050856 | 0.85 | TAAR1 (0.74) | TAAR1PNMTAOC3HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1281 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250092050-A1 | 1-AMINOBENZO[4,5]IMIDAZO[1,2-A]PYRAZINE-3-FORMAMIDE COMPOUND, AND PREPARATION THEREFOR AND USE THEREOF | SUN YAT-SEN UNIVERSITY (CN) | 2025-03-20 | — | — | US | claimed |
| EP-4461733-A1 | 1-AMINOBENZO[4,5]IMIDAZO[1,2-A]PYRAZINE-3-FORMAMIDE COMPOUND, AND PREPARATION THEREFOR AND USE THEREOF | Sun Yat-Sen University (CN) | 2024-11-13 | — | — | EP | claimed |
| CN-118726998-A | Preparation method for preparing benzyl carboxylic acid compound from benzylamine and carbon dioxide | 哈尔滨工业大学（深圳） | 2024-10-01 | — | — | CN | claimed |
| US-20240199542-A1 | SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2024-06-20 | — | — | US | claimed |
| EP-4313943-A1 | SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2024-02-07 | — | — | EP | claimed |
| CN-117442609-A | Application of tetrahydrocarbazole derivative in preventing and treating cow mastitis pathogenic bacteria | 兰州大学 | 2024-01-26 | — | — | CN | claimed |
| CN-117281120-A | Application of tetrahydrocarbazole derivative in preventing and controlling agricultural bacterial diseases | 兰州大学 | 2023-12-26 | — | — | CN | claimed |
| CN-117082953-A | Optoelectronic device and method for producing the same | 天合光能股份有限公司 | 2023-11-17 | — | — | CN | claimed |
| CN-116813497-B | Amide compound and preparation method, pharmaceutical composition and application thereof | 天津匠新致成科技有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-116497525-B | Preparation method of heat insulation felt | 安徽弘昌新材料股份有限公司 | 2023-09-22 | — | — | CN | claimed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | claimed |
| WO-1999037304-A1 | SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 1999-07-29 | — | — | WO | claimed |
| EP-0863877-A4 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INST (US) | 1999-07-21 | — | — | EP | claimed |
| US-5874443-A | BIOSYNTHESIS | TREGA BIOSCIENCES, INC. (US) | 1999-02-23 | — | — | US | claimed |
| EP-0863877-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1998-09-16 | — | — | EP | claimed |
| WO-1997016428-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1997-05-09 | — | — | WO | claimed |
| EP-0403360-A2 | Use of phenylethanolamines for the preparation of a medicament for treating ophthalmologic disorders | SANOFI (FR) | 1990-12-19 | — | — | EP | claimed |
| EP-0262785-A1 | N-[2-(4-carboxymethoxyphenyl)-1-methylethyl]-2-hydroxy-2-(3-chlorophenyl)ethane amine, the methyl ester, salt and stereoisomeric forms thereof | BEECHAM GROUP PLC (GB) | 1988-04-06 | — | — | EP | claimed |
| EP-0255415-A2 | Use of phenylethanolamines for the preparation of medicaments acting on gastrointestinal troubles | ELF SANOFI (FR) | 1988-02-03 | — | — | EP | claimed |
| EP-0052963-B1 | SECONDARY AMINES | BEECHAM GROUP PLC (GB) | 1985-02-20 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250092050-A1 | 1-AMINOBENZO[4,5]IMIDAZO[1,2-A]PYRAZINE-3-FORMAMIDE COMPOUND, AND PREPARATION THEREFOR AND USE THEREOF | ADORA1, ADORA2A, ADORA2B | TAAR1 783/4885PNMT 3184/4885MAOB 754/4885 |
| US-20240199542-A1 | SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | HPD, DDT, PPOX | TAAR1 3744/4885PNMT 755/4885MAOB 702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.