SCHEMBL148755

SCHEMBL148755

Cc1ccc(CO)cc1CO

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.48
HSD17B10 Q99714 1/20 0.41
KDM4E B2RXH2 1/20 0.40
CASP6 P55212 1/20 0.40
EGFR P00533 1/20 0.40
MAPT P10636 1/20 0.39
S1PR1 P21453 3/20 0.39
HPGD P15428 1/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
PKM P14618 1/20 0.36
VDR P11473 1/20 0.36
CYP4F2 P78329 1/20 0.36
CYP4A11 Q02928 1/20 0.36
TSHR P16473 1/20 0.36
RECQL P46063 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
ENPP2 Q13822 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29741490 1.00 SHBG (0.48) SHBGHSD17B10KDM4ECASP6EGFR
SCHEMBL11967053 0.89 BACE1 (0.40) SHBGHSD17B10KDM4ECASP6EGFR
SCHEMBL13386105 0.87 TAAR1 (0.39) SHBGHSD17B10EGFRS1PR1ESR1
SCHEMBL8773463 0.86 TRPA1 (0.46) SHBGS1PR1HPGDPKMVDR
SCHEMBL8065632 0.83 SHBG (0.47) SHBGHSD17B10KDM4ECASP6EGFR
SCHEMBL18007124 0.82 CNR1 (0.48) SHBGS1PR1VDRTAAR1
SCHEMBL93048 0.82 S1PR1 (0.47) SHBGHSD17B10S1PR1ESR1ESR2
SCHEMBL11158364 0.82 CYP4F2 (0.40) SHBGHSD17B10EGFRHPGDPKM
SCHEMBL8973742 0.82 S1PR1 (0.36) SHBGHSD17B10KDM4ES1PR1ESR1
SCHEMBL658608 0.82 KLKB1 (0.43) HSD17B10KDM4EEGFRMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1141207-B1 TRANSPARENT/TRANSLUCENT LIQUID ENZYME COMPOSITIONS IN CLEAR BOTTLES COMPRISING FLUORESCENT DYE OR UV ABSORBER UNILEVER NV (NL) 2004-02-04 EP claimed
US-12595251-B2 Amidines and amidine analogs for the treatment of bacterial infections and potentiation antibiotics GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2026-04-07 US disclosed
EP-4711519-A1 SYNTHETIC LEATHER AND METHOD FOR PRODUCING SYNTHETIC LEATHER DIC Corporation (JP) 2026-03-18 EP disclosed
EP-4603484-A2 COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION OF ANTIBIOTICS Georgia State University Research Foundation, Inc. (US) 2025-08-20 EP disclosed
EP-4384593-A1 METHOD OF TREATING A FABRIC WITH DELIVERY PARTICLES The Procter & Gamble Company (US) 2024-06-19 EP disclosed
EP-4377428-A1 LAUNDRY DETERGENT PRODUCT Unilever IP Holdings B.V. (NL) 2024-06-05 EP disclosed
US-20230407208-A1 LAUNDRY DETERGENT PRODUCT CONOPCO, INC., D/B/A UNILEVER (US) 2023-12-21 US disclosed
WO-2023233025-A1 LIQUID DETERGENT PRODUCT UNILEVER IP HOLDINGS B.V. (NL) 2023-12-07 WO disclosed
WO-2023233026-A1 LAUNDRY DETERGENT PRODUCT UNILEVER IP HOLDINGS B.V. (NL) 2023-12-07 WO disclosed
WO-2023233028-A1 LAUNDRY DETERGENT PRODUCT UNILEVER IP HOLDINGS B.V. (NL) 2023-12-07 WO disclosed
US-4438178-A COATED WITH EPICHLOROHYDRIN ETHER OR ESTER FIBER INDUSTRIES, INC. (US) 1984-03-20 US disclosed
US-4302272-A HEATING SURFACE OF A POLYETHERURETHANE ABOVE ITS MELTING POINT FOLLOWED BY COOLING MOBAY CHEMICAL CORPORATION (US) 1981-11-24 US disclosed
US-4282332-A POLYURETHANES MOBAY CHEMICAL CORPORATION (US) 1981-08-04 US disclosed
US-4240974-A 1,2,3,4,9,9-HEXAHALO-1,4-DIHYDRO-1,4-METHANO-NAPHTHALENE-5,8 -DISULFONATE LITTLE JULIAN R (US) 1980-12-23 US disclosed
US-4234745-A Polyols derived from 4,4,4-trichloro-1,2-epoxybutane and/or epihalohydrin for use in the production of heat sealable foams MOBAY CHEMICAL CORPORATION (US) 1980-11-18 US disclosed
US-4174457-A Carbamate UNIROYAL, INC. (US) 1979-11-13 US disclosed
US-4080408-A FIRE RETARDANTS UNIROYAL, INC. (US) 1978-03-21 US disclosed
US-4058568-A FIRE RETARDANT UNIROYAL, INC. (US) 1977-11-15 US disclosed
US-4009200-A FIREPROOFING POLYMERS UNIROYAL, INC. (US) 1977-02-22 US disclosed
US-3947471-A CHROMOGENIC SUMITOMO CHEMICAL COMPANY, LTD. (JA) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595251-B2 Amidines and amidine analogs for the treatment of bacterial infections and potentiation antibiotics CLIC1, CBR3, CBR1 SHBG 4747/4885HSD17B10 1689/4885KDM4E 4720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.