SCHEMBL1487612

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8320544	0.84	MAP3K11 (0.78)	MAPK8MAPK9MAPK10MAP3K11NTRK1
	SCHEMBL8321012	0.83	MAPK8 (0.63)	MAPK8MAPK9MAPK10MAP3K11NTRK1
	SCHEMBL13753917	0.83	MAPK8 (0.63)	MAPK8MAPK9MAPK10MAP3K11NTRK1
	SCHEMBL13620697	0.82	AXL (0.76)	MAPK8MAPK9MAPK10MAP3K11NTRK1
	SCHEMBL8298162	0.81	MAPK8 (0.72)	MAPK8MAPK9MAPK10MAP3K11NTRK1
	SCHEMBL12829259	0.81	NTRK1 (0.66)	MAP3K11NTRK1DYRK1ACLK1DYRK2
	SCHEMBL20408723	0.81	KIT (0.59)	NTRK1DYRK1ACLK1DYRK2DYRK1B
	SCHEMBL8320542	0.81	DYRK1A (0.59)	MAP3K11NTRK1DYRK1ACLK1DYRK2
	SCHEMBL8249652	0.81	MAPK8 (0.60)	MAPK8MAPK9MAPK10MAP3K11NTRK1
	SCHEMBL4200987	0.81	MAPK8 (0.60)	MAPK8MAPK9MAPK10MAP3K11NTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.