Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 1.00 |
| ▸ | ITGAV | P06756 | 1/20 | 1.00 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.65 |
| ▸ | FAAH | O00519 | 1/20 | 0.64 |
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.60 |
| ▸ | ACP1 | P24666 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | AURKA | O14965 | 2/20 | 0.57 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.57 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.57 |
| ▸ | FABP4 | P15090 | 1/20 | 0.55 |
| ▸ | CSF1R | P07333 | 1/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.54 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.54 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14876908 | 1.00 | ITGB3 (1.00) | ITGB3ITGAVPTP4A3FAAHPPARG | |
| SCHEMBL12717615 | 1.00 | ITGB3 (1.00) | ITGB3ITGAVPTP4A3FAAHPPARG | |
| SCHEMBL14876910 | 1.00 | ITGB3 (1.00) | ITGB3ITGAVPTP4A3FAAHPPARG | |
| SCHEMBL14883359 | 1.00 | ITGB3 (1.00) | ITGB3ITGAVPTP4A3FAAHPPARG | |
| SCHEMBL12717769 | 0.93 | ITGB3 (0.86) | ITGB3ITGAVPTP4A3FAAHPPARG | |
| SCHEMBL16000777 | 0.92 | ITGB3 (0.85) | ITGB3ITGAVPTP4A3FAAHPPARG | |
| SCHEMBL23519101 | 0.79 | MEN1 (0.68) | ITGB3ITGAVPTPN1ACP1ALDH1A1 | |
| SCHEMBL30117305 | 0.79 | PTP4A3 (1.00) | ITGB3ITGAVPTP4A3PPARGALDH1A1 | |
| SCHEMBL19481522 | 0.79 | FAAH (0.84) | ITGB3ITGAVFAAHCA9ALDH1A1 | |
| SCHEMBL19485870 | 0.79 | FAAH (0.84) | ITGB3ITGAVFAAHCA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140249191-A1 | Compositions for Controlling Vascularization in Ophthalmological and Dermatological Diseases | AVIENNE PHARMACEUTICALS GMBH (AT) | 2014-09-04 | — | — | US | disclosed |
| US-20130102645-A1 | Methods and compositions for controlling vascularization in ophthalmological and dermatological diseases | AVIENNE PHARMACEUTICALS GMBH (AT) | 2013-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102645-A1 | Methods and compositions for controlling vascularization in ophthalmological and dermatological diseases | KDR, REN, FLT1 | ITGB3 2036/4885ITGAV 1978/4885PTP4A3 399/4885 |
| US-20140249191-A1 | Compositions for Controlling Vascularization in Ophthalmological and Dermatological Diseases | FLT1, KDR, FLT4 | ITGB3 2012/4885ITGAV 1557/4885PTP4A3 742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.