Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | RARB | P10826 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | TACR2 | P21452 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11013515 | 0.97 | KDM4E (0.49) | KDM4ERAB9ARARBHSD17B10TSHR | |
| SCHEMBL11015834 | 0.90 | KDM4E (0.49) | KDM4ERAB9ARARBHSD17B10TSHR | |
| SCHEMBL11017540 | 0.90 | KDM4E (0.49) | KDM4ERAB9ARARBHSD17B10TSHR | |
| SCHEMBL11016961 | 0.89 | KDM4E (0.44) | KDM4ERAB9ARARBHSD17B10TSHR | |
| SCHEMBL11015800 | 0.89 | HSD17B10 (0.51) | KDM4ERAB9ARARBHSD17B10TSHR | |
| SCHEMBL6421748 | 0.89 | HSD17B10 (0.53) | KDM4ERAB9ARARBHSD17B10TSHR | |
| SCHEMBL6422261 | 0.89 | HSD17B10 (0.53) | KDM4ERAB9ARARBHSD17B10TSHR | |
| SCHEMBL1231095 | 0.89 | HSD17B10 (0.53) | KDM4ERAB9ARARBHSD17B10TSHR | |
| SCHEMBL4449126 | 0.89 | HSD17B10 (0.53) | KDM4ERAB9ARARBHSD17B10TSHR | |
| SCHEMBL14703081 | 0.87 | HSD17B10 (0.56) | KDM4ERAB9ARARBHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915609-B2 | Smectic liquid crystal compound | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2011-03-29 | — | — | US | disclosed |
| US-7915609-B2 | Smectic liquid crystal compound | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2011-03-29 | — | — | US | disclosed |
| US-20100237327-A1 | SMECTIC LIQUID CRYSTAL COMPOUND | NAT. INSTIUTE OF ADV. INDUSTRIAL SCI. AND TECH. (JP) | 2010-09-23 | — | — | US | disclosed |
| US-20100237327-A1 | SMECTIC LIQUID CRYSTAL COMPOUND | NAT. INSTIUTE OF ADV. INDUSTRIAL SCI. AND TECH. (JP) | 2010-09-23 | — | — | US | disclosed |
| EP-2036900-A1 | SMECTIC LIQUID CRYSTAL COMPOUND | National Institute Of Advanced Industrial Science and Technology (JP) | 2009-03-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100237327-A1 | SMECTIC LIQUID CRYSTAL COMPOUND | CNOT1, SLC43A1, CNOT9 | KDM4E 2711/4885RAB9A 578/4885RARB 3721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.