SCHEMBL1487708

SCHEMBL1487708

c1ccc(-c2ccsc2-c2ccsc2-c2cccs2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.45
PTPRC P08575 1/20 0.40
BCAT2 O15382 1/20 0.40
ADORA2A P29274 3/20 0.39
ADORA1 P30542 3/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2E1 P05181 1/20 0.39
CYP2A6 P11509 1/20 0.39
CYP2B6 P20813 1/20 0.39
KDM4E B2RXH2 4/20 0.38
MAPT P10636 4/20 0.38
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
ALDH1A1 P00352 3/20 0.38
HPGD P15428 3/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38
PPARG P37231 1/20 0.38
NCOA2 Q15596 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28641765 0.96 PTGS2 (0.46) PTGS2PTPRCBCAT2ADORA2AADORA1
SCHEMBL7802382 0.96 PTGS2 (0.47) PTGS2PTPRCBCAT2ADORA2AADORA1
Benzene SCHEMBL27761468 0.96 PTGS2 (0.47) PTGS2PTPRCBCAT2ADORA2AADORA1
SCHEMBL21295467 0.93 PTGS2 (0.49) PTGS2PTPRCBCAT2ADORA2AADORA1
SCHEMBL22734807 0.84 PTPRC (0.41) PTPRCADORA2AADORA1CYP3A4CYP2C9
SCHEMBL22763310 0.84 PTPRC (0.41) PTPRCADORA2AADORA1CYP3A4CYP2C9
SCHEMBL22734786 0.84 PTPRC (0.41) PTPRCADORA2AADORA1CYP3A4CYP2C9
SCHEMBL22734772 0.84 PTPRC (0.41) PTPRCADORA2AADORA1CYP3A4CYP2C9
SCHEMBL22763791 0.84 PTPRC (0.41) PTPRCADORA2AADORA1CYP3A4CYP2C9
SCHEMBL16872440 0.84 ALOX5 (0.41) PTGS2PTPRCBCAT2ADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7915609-B2 Smectic liquid crystal compound NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2011-03-29 US disclosed
US-20100237327-A1 SMECTIC LIQUID CRYSTAL COMPOUND NAT. INSTIUTE OF ADV. INDUSTRIAL SCI. AND TECH. (JP) 2010-09-23 US disclosed
EP-2036900-A1 SMECTIC LIQUID CRYSTAL COMPOUND National Institute Of Advanced Industrial Science and Technology (JP) 2009-03-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100237327-A1 SMECTIC LIQUID CRYSTAL COMPOUND CNOT1, SLC43A1, CNOT9 PTGS2 4803/4885PTPRC 3610/4885BCAT2 1415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.