SCHEMBL14877508

SCHEMBL14877508

C=CCN1C2C3N(CC=C)C1C1N(CC=C)C(C(N1CC=C)N3CC=C)N2CC=C

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
CYP3A4 P08684 1/20 0.36
PRCP P42785 1/20 0.32
ADRA1D P25100 1/20 0.30
ADRA1A P35348 1/20 0.30
ADRA1B P35368 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12341628 0.78
SCHEMBL12342445 0.76
SCHEMBL15662580 0.76 CYP3A4 (0.35) ALDH1A1CYP3A4PRCP
SCHEMBL308887 0.73 CYP3A4 (0.33) ALDH1A1CYP3A4PRCP
SCHEMBL10472229 0.73 CYP3A4 (0.33) ALDH1A1CYP3A4PRCP
SCHEMBL16136767 0.72 CYP3A4 (0.30) CYP3A4
SCHEMBL2107918 0.71 CYP3A4 (0.32) CYP3A4
SCHEMBL16767751 0.66 CHRNB2 (0.37) PRCP
SCHEMBL7356765 0.66 LMNA (0.36) ALDH1A1CYP3A4
SCHEMBL2107962 0.66 PRCP (0.31) PRCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426582-B1 Processes for preparing certain hexaazaisowurtzitanes and their use in preparing hexanitrohexaazaisowurtzitane THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2013-04-23 US disclosed
US-8426582-B1 Processes for preparing certain hexaazaisowurtzitanes and their use in preparing hexanitrohexaazaisowurtzitane THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2013-04-23 US disclosed