Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.53 |
| ▸ | DDT | P30046 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 3/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.46 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24573376 | 0.82 | GRM2 (0.45) | BCAT2IKBKBMKNK1CHEK2GRM2 | |
| SCHEMBL9930222 | 0.82 | CNR2 (0.47) | BCAT2MKNK1CHEK2GRM2CASP1 | |
| SCHEMBL686861 | 0.79 | DDT (0.74) | DDTALDH1A1 | |
| SCHEMBL29914342 | 0.79 | DDT (0.74) | DDTALDH1A1 | |
| SCHEMBL19260814 | 0.75 | GRM2 (0.52) | PARP1GRM2NPC1RAB9A | |
| SCHEMBL9002495 | 0.74 | SIRT6 (0.47) | PARP1 | |
| SCHEMBL23846485 | 0.72 | BCAT2 (0.61) | BCAT2PARP1IKBKBMKNK1CHUK | |
| SCHEMBL29735324 | 0.72 | PLAU (0.54) | IKBKBMKNK1CHUKIKBKEPKMYT1 | |
| SCHEMBL2927582 | 0.72 | HIF1A (0.53) | PARP1MKNK1CHEK2MKNK2ALDH1A1 | |
| SCHEMBL2935534 | 0.72 | PLAU (0.54) | IKBKBMKNK1CHUKIKBKEPKMYT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426368-B2 | Method of ameliorating oxidative stress and supplementing the diet | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2013-04-23 | — | — | US | disclosed |