Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.53 |
| ▸ | MMP9 | P14780 | 3/20 | 0.53 |
| ▸ | MMP13 | P45452 | 3/20 | 0.53 |
| ▸ | MMP3 | P08254 | 2/20 | 0.53 |
| ▸ | MMP7 | P09237 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12905490 | 0.92 | MMP1 (0.51) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL14878468 | 0.91 | MMP1 (0.41) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL778947 | 0.91 | MMP1 (0.66) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL6851780 | 0.87 | FNTA (0.46) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL16507897 | 0.86 | MMP1 (0.64) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL14878420 | 0.85 | MMP1 (0.51) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL12905437 | 0.83 | MMP1 (0.40) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL14878438 | 0.81 | CNR1 (0.38) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL778858 | 0.81 | MMP1 (0.53) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL14878439 | 0.81 | MMP3 (0.40) | MMP1MMP9MMP13MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426415-B2 | Human ADAM-10 inhibitors | SYMPHONY EVOLUTION, INC. (US) | 2013-04-23 | — | — | US | disclosed |