Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17775982 | 0.86 | TRPV4 (0.36) | TRPV4NR1I2CYP2C9MLYCDPDE2A | |
| SCHEMBL14451426 | 0.83 | PTPN5 (0.36) | TRPV4NR1I2CYP2C9MLYCDPDE2A | |
| SCHEMBL30521437 | 0.83 | PTPN5 (0.36) | TRPV4NR1I2CYP2C9MLYCDPDE2A | |
| SCHEMBL21377045 | 0.83 | TRPV4 (0.38) | TRPV4NR1I2CYP2C9MLYCDPDE2A | |
| SCHEMBL13262415 | 0.79 | TRPV4 (0.32) | TRPV4NR1I2CYP2C9MLYCD | |
| SCHEMBL17775927 | 0.74 | TRPV4 (0.36) | TRPV4NR1I2CYP2C9MLYCDPDE2A | |
| SCHEMBL19619488 | 0.73 | TRPV4 (0.39) | TRPV4NR1I2CYP2C9MLYCDPDE2A | |
| SCHEMBL15603407 | 0.73 | TRPV4 (0.48) | TRPV4NR1I2CYP2C9PDE2A | |
| SCHEMBL27841661 | 0.73 | TRPV4 (0.48) | TRPV4NR1I2CYP2C9PDE2A | |
| SCHEMBL16116586 | 0.73 | GPR55 (0.32) | NR1I2CYP2C9KCNH2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351740-B1 | Insecticidal composition comprising N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines | DOW AGROSCIENCES LLC (US) | 2013-04-24 | — | — | EP | disclosed |