Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 8/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12057611 | 0.79 | KIF11 (0.53) | KIF11ALDH1A1TSHRCNR2CNR1 | |
| SCHEMBL12057593 | 0.79 | KIF11 (0.53) | KIF11ALDH1A1TSHRCNR2CNR1 | |
| SCHEMBL12057618 | 0.79 | KIF11 (0.53) | KIF11ALDH1A1TSHRCNR2CNR1 | |
| SCHEMBL21597132 | 0.73 | FLT3 (0.67) | KIF11ALDH1A1TSHRCNR2CNR1 | |
| SCHEMBL21603653 | 0.72 | FLT3 (0.68) | KIF11ALDH1A1TSHRCNR2CNR1 | |
| SCHEMBL20354020 | 0.69 | TP53 (0.56) | MEN1KMT2AMAPTTP53 | |
| SCHEMBL16210887 | 0.68 | KMT2A (0.74) | KIF11ALDH1A1CNR2CNR1MEN1 | |
| SCHEMBL14156287 | 0.67 | ALDH1A1 (0.53) | KIF11ALDH1A1TSHRCNR2CNR1 | |
| SCHEMBL12057608 | 0.66 | ALDH1A1 (0.64) | KIF11ALDH1A1TSHRCNR2MEN1 | |
| SCHEMBL12057594 | 0.66 | ALDH1A1 (0.64) | KIF11ALDH1A1TSHRCNR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2583963-A1 | Proline analogs as ligands for cannabinoid receptors for the treatment of pain | Purdue Pharma L.P. (US) | 2013-04-24 | — | — | EP | disclosed |