SCHEMBL12609455

SCHEMBL12609455

CC(=O)O/N=C1\COc2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.44
MAPT P10636 6/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
KDM4E B2RXH2 4/20 0.40
HPGD P15428 4/20 0.40
GAA P10253 3/20 0.40
HSD17B10 Q99714 3/20 0.40
MAPK1 P28482 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
TSHR P16473 2/20 0.40
ATM Q13315 2/20 0.40
GLA P06280 1/20 0.40
CASP1 P29466 1/20 0.40
CASP7 P55210 1/20 0.40
MAOB P27338 2/20 0.38
MAOA P21397 1/20 0.38
RAB9A P51151 2/20 0.38
NOTUM Q6P988 1/20 0.38
NPC1 O15118 1/20 0.38
ALOX12 P18054 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12609459 0.85 NOTUM (0.43) ALDH1A1MAPTSMN1; SMN2KDM4EHPGD
SCHEMBL19308414 0.81 L3MBTL1 (0.45) ALDH1A1MAPTSMN1; SMN2KDM4EHPGD
SCHEMBL18924655 0.78 MIF (0.40) ALDH1A1MAPTSMN1; SMN2KDM4EHPGD
SCHEMBL6656648 0.78 MIF (0.40) ALDH1A1MAPTSMN1; SMN2KDM4EHPGD
SCHEMBL6653939 0.78 MIF (0.40) ALDH1A1MAPTSMN1; SMN2KDM4EHPGD
SCHEMBL18328443 0.77 NPC1 (0.43) ALDH1A1MAPTKDM4EGAAL3MBTL1
SCHEMBL12609476 0.77 CYP19A1 (0.40) ALDH1A1MAPTSMN1; SMN2KDM4EHPGD
SCHEMBL12110618 0.75 CA12 (0.34) ALDH1A1MAPTKDM4EHPGDHSD17B10
SCHEMBL13130686 0.74 MAPT (0.35) ALDH1A1MAPTSMN1; SMN2KDM4EHPGD
SCHEMBL4418795 0.74 LMNA (0.55) ALDH1A1MAPTSMN1; SMN2KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120282549-A1 PHOTOSENSITIVE COMPOSITION, PHOTOSENSITIVE FILM, PHOTOSENSITIVE LAMINATE, METHOD FOR FORMING PERMANENT PATTERN, AND PRINTED BOARD FUJIFILM CORPORATION (JP) 2012-11-08 US disclosed
US-20120282549-A1 PHOTOSENSITIVE COMPOSITION, PHOTOSENSITIVE FILM, PHOTOSENSITIVE LAMINATE, METHOD FOR FORMING PERMANENT PATTERN, AND PRINTED BOARD FUJIFILM CORPORATION (JP) 2012-11-08 US disclosed
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT FUJIFILM CORPORATION (JP) 2011-05-26 US disclosed
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT FUJIFILM CORPORATION (JP) 2011-05-26 US disclosed
US-20100015352-A1 INK-JET INK COMPOSITION, AND INK-JET RECORDING METHOD FUJIFILM CORPORATION (JP) 2010-01-21 US disclosed
US-20100015352-A1 INK-JET INK COMPOSITION, AND INK-JET RECORDING METHOD FUJIFILM CORPORATION (JP) 2010-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110123929-A1 OXIME COMPOUND, PHOTOSENSITIVE COMPOSITION, COLOR FILTER, PRODUCTION METHOD FOR THE COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT PPOX, CRY2, HCCS ALDH1A1 1226/4885MAPT 3766/4885SMN1; SMN2 4176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.