SCHEMBL14879624

SCHEMBL14879624

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nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
TSHR P16473 1/20 0.38
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27605912 0.79
SCHEMBL27623376 0.79 KEAP1 (0.31)
Hydrochloric Acid SCHEMBL27605906 0.78
SCHEMBL28262576 0.77
SCHEMBL3874816 0.77
SCHEMBL3861981 0.77
SCHEMBL3874819 0.77
SCHEMBL2241969 0.77
Hydrochloric Acid SCHEMBL5498424 0.76 TSHR (0.37) TSHRHSD17B10
SCHEMBL6590939 0.74 ALOX15 (0.41) ALDH1A1TSHRHSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140249076-A1 AMYLIN-CALCITONIN CHIMERIC PEPTIDES CONJUGATED TO DURATION ENHANCING MOIETIES ASTRAZENECA PHARMACEUTICALS LP 2014-09-04 US disclosed
WO-2013059336-A1 AMYLIN-CALCITONIN CHIMERIC PEPTIDES CONJUGATED TO DURATION ENCHANCING MOIETIES AMYLIN PHARMACEUTICALS, LLC (US) 2013-04-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140249076-A1 AMYLIN-CALCITONIN CHIMERIC PEPTIDES CONJUGATED TO DURATION ENHANCING MOIETIES IAPP, GIPR, VIP ALDH1A1 3723/4885TSHR 1233/4885HSD17B10 2504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.