Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.64 |
| ▸ | CES1 | P23141 | 1/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.63 |
| ▸ | MMP1 | P03956 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5440164 | 0.94 | HDAC1 (0.63) | CES2CES1HDAC6HDAC3HDAC8 | |
| SCHEMBL21628873 | 0.89 | MAPK14 (0.58) | CES2CES1HDAC6HDAC3HDAC8 | |
| SCHEMBL674439 | 0.89 | HDAC6 (0.82) | HDAC6HDAC3HDAC8HDAC2TRPV1 | |
| SCHEMBL6572354 | 0.84 | HDAC6 (0.72) | HDAC6HDAC3HDAC8HDAC1HDAC2 | |
| SCHEMBL3673435 | 0.83 | HDAC6 (0.75) | HDAC6HDAC3HDAC8HDAC1HDAC2 | |
| SCHEMBL4174548 | 0.82 | CES2 (0.64) | CES2CES1MMP1SRD5A2TRPV1 | |
| SCHEMBL3609887 | 0.82 | HDAC6 (0.61) | HDAC6HDAC3HDAC8HDAC1HDAC2 | |
| SCHEMBL15850886 | 0.80 | LMNA (0.79) | HDAC6HDAC3HDAC8HDAC2 | |
| SCHEMBL14880119 | 0.80 | HDAC6 (0.72) | CES2HDAC6HDAC3HDAC8HDAC1 | |
| SCHEMBL8578258 | 0.80 | CES2 (0.61) | CES2CES1SRD5A2TRPV1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119176819-B | Method for preparing 3, 6-dihydro-1, 2-oxazine derivative by iodine catalysis in aqueous phase | 山东第二医科大学 | 2025-02-14 | — | — | CN | claimed |
| CN-119176819-A | Method for preparing 3, 6-dihydro-1, 2-oxazine derivative by iodine catalysis in aqueous phase | 山东第二医科大学 | 2024-12-24 | — | — | CN | claimed |
| CN-119176819-B | Method for preparing 3, 6-dihydro-1, 2-oxazine derivative by iodine catalysis in aqueous phase | 山东第二医科大学 | 2025-02-14 | — | — | CN | disclosed |
| CN-119176819-A | Method for preparing 3, 6-dihydro-1, 2-oxazine derivative by iodine catalysis in aqueous phase | 山东第二医科大学 | 2024-12-24 | — | — | CN | disclosed |
| CN-118652153-A | Method for synthesizing organic nitrile compound from aldehyde | 国科大杭州高等研究院 | 2024-09-17 | — | — | CN | disclosed |
| CN-115160097-B | Method for synthesizing amide by reducing N-O bond by thioacetic acid | 温州大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-114933573-B | 3-substituted-1, 2, 4-oxadiazole-5-carboxylic acid derivative, and preparation method and application thereof | 贵州大学 | 2023-10-20 | — | — | CN | disclosed |
| CN-115093377-B | Haloalkyl-containing 1,2, 4-oxadiazole derivative and preparation method and application thereof | 贵州大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-115160097-A | Method for reducing N-O bonding into amide by thioacetic acid | 温州大学 | 2022-10-11 | — | — | CN | disclosed |
| CN-115093377-A | Haloalkyl-containing 1,2, 4-oxadiazole derivative and preparation method and application thereof | 贵州大学 | 2022-09-23 | — | — | CN | disclosed |
| CN-114933573-A | 3-substituted-1, 2, 4-oxadiazole-5-carboxylic acid derivative, and preparation method and application thereof | 贵州大学 | 2022-08-23 | — | — | CN | disclosed |
| WO-2013059582-A2 | SMALL MOLECULE INHIBITORS OF HISTONE DEACTEYLASES | NUPOTENTIAL, INC. (US) | 2013-04-25 | — | — | WO | disclosed |