Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.58 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20328415 | 0.88 | APP (0.70) | KCNJ1KCNH2APPALDH1A1LMNA | |
| SCHEMBL20328414 | 0.88 | APP (0.70) | KCNJ1KCNH2APPALDH1A1LMNA | |
| SCHEMBL492221 | 0.88 | APP (0.70) | KCNJ1KCNH2APPALDH1A1LMNA | |
| SCHEMBL28853641 | 0.86 | APP (0.68) | KCNJ1KCNH2APPALDH1A1LMNA | |
| Ethane SCHEMBL10589507 | 0.86 | APP (0.68) | KCNJ1KCNH2APPALDH1A1LMNA | |
| SCHEMBL31096483 | 0.86 | APP (0.68) | KCNJ1KCNH2APPALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL15269629 | 0.86 | APP (0.68) | KCNJ1KCNH2APPALDH1A1LMNA | |
| SCHEMBL27548370 | 0.86 | APP (0.68) | KCNJ1KCNH2APPALDH1A1LMNA | |
| SCHEMBL21753948 | 0.86 | KCNJ1 (0.60) | KCNJ1KCNH2APPALDH1A1LMNA | |
| SCHEMBL28131042 | 0.85 | NFE2L2 (0.58) | ALDH1A1LMNAMAPTRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105949178-A | Benzimidazole compound, and preparation method, intermediate and application thereof | 张锐豪 | 2016-09-21 | — | — | CN | disclosed |
| EP-2780326-A1 | METHOD FOR INHIBITION OF DEUBIQUITINATING ACTIVITY | Vivolux Ab (SE) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013058691-A1 | METHOD FOR INHIBITION OF DEUBIQUITINATING ACTIVITY | VIVOLUX AB (SE) | 2013-04-25 | — | — | WO | disclosed |